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Andrew D Davidson

Explore the profile of Andrew D Davidson including associated specialties, affiliations and a list of published articles. Areas
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Articles 72
Citations 3315
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Recent Articles
1.
Webb I, Erdmann M, Milligan R, Savage M, Matthews D, Davidson A
J Gen Virol . 2025 Feb; 106(2). PMID: 39937571
The SARS-CoV-2 genome encodes at least nine accessory proteins, including innate immune antagonist and putative viroporin ORF3a. ORF3a plays a role in many stages of the viral replication cycle, including...
2.
Erdmann M, Hodgson L, Webb I, Davidson A, Verkade P
Methods Cell Biol . 2024 May; 187:99-116. PMID: 38705632
Correlative Light Electron Microscopy (CLEM) is a powerful technique to investigate the ultrastructure of specific cells and organelles at sub-cellular resolution. Transmission Electron Microscopy (TEM) is particularly useful to the...
3.
Haddrell A, Oswin H, Otero-Fernandez M, Robinson J, Cogan T, Alexander R, et al.
Nat Commun . 2024 Apr; 15(1):3487. PMID: 38664424
An improved understanding of the underlying physicochemical properties of respiratory aerosol that influence viral infectivity may open new avenues to mitigate the transmission of respiratory diseases such as COVID-19. Previous...
4.
Bigotti M, Klein K, Gan E, Anastasina M, Andersson S, Vapalahti O, et al.
Antiviral Res . 2024 Feb; 224:105837. PMID: 38387750
The COVID-19 pandemic has shown the need to develop effective therapeutics in preparedness for further epidemics of virus infections that pose a significant threat to human health. As a natural...
5.
Buzas D, Bunzel A, Staufer O, Milodowski E, Edmunds G, Bufton J, et al.
Antib Ther . 2023 Dec; 6(4):277-297. PMID: 38075238
Background: Due to COVID-19, pandemic preparedness emerges as a key imperative, necessitating new approaches to accelerate development of reagents against infectious pathogens. Methods: Here, we developed an integrated approach combining...
6.
Gallucci L, Bazire J, Davidson A, Shytaj I
Antiviral Res . 2023 Dec; 221:105766. PMID: 38042417
Coronaviruses pose a permanent risk of outbreaks, with three highly pathogenic species and strains (SARS-CoV, MERS-CoV, SARS-CoV-2) having emerged in the last twenty years. Limited antiviral therapies are currently available...
7.
Stewart H, Lu Y, OKeefe S, Valpadashi A, Cruz-Zaragoza L, Michel H, et al.
iScience . 2023 Oct; 26(11):108080. PMID: 37860693
The SARS-CoV-2 genome encodes a multitude of accessory proteins. Using comparative genomic approaches, an additional accessory protein, ORF3c, has been predicted to be encoded within the ORF3a sgmRNA. Expression of...
8.
Haddrell A, Otero-Fernandez M, Oswin H, Cogan T, Bazire J, Tian J, et al.
J R Soc Interface . 2023 Jun; 20(203):20230062. PMID: 37340783
The mechanistic factors hypothesized to be key drivers for the loss of infectivity of viruses in the aerosol phase often remain speculative. Using a next-generation bioaerosol technology, we report measurements...
9.
Santopaolo M, Gregorova M, Hamilton F, Arnold D, Long A, Lacey A, et al.
Elife . 2023 Jun; 12. PMID: 37310006
Coronavirus disease-19 (COVID-19) causes immune perturbations which may persist long term, and patients frequently report ongoing symptoms for months after recovery. We assessed immune activation at 3-12 months post hospital...
10.
Wing P, Schmidt N, Peters R, Erdmann M, Brown R, Wang H, et al.
PLoS Pathog . 2023 May; 19(5):e1011323. PMID: 37134108
The severity of disease following infection with SARS-CoV-2 is determined by viral replication kinetics and host immunity, with early T cell responses and/or suppression of viraemia driving a favourable outcome....