A Hallberg
Overview
Explore the profile of A Hallberg including associated specialties, affiliations and a list of published articles.
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93
Citations
921
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Recent Articles
11.
Olofsson K, Sahlin H, Larhed M, Hallberg A
J Org Chem
. 2001 Jun;
66(2):544-9.
PMID: 11429827
A highly regioselective Heck arylation, utilizing aryl triflates and a palladium/dppf catalytic system, can be performed at the internal, beta-carbon of Boc- and phthalimido-protected allylamines, yielding arylated primary allylamine equivalents....
12.
Vallin K, Larhed M, Hallberg A
J Org Chem
. 2001 Jun;
66(12):4340-3.
PMID: 11397173
Highly selective palladium-catalyzed internal alpha-arylations of alkyl vinyl ethers with aryl and heteroaryl bromides were conveniently conducted in aqueous DMF with potassium carbonate as base and with DPPP as bidentate...
13.
Lindman S, Lindeberg G, Gogoll A, Nyberg F, Karlen A, Hallberg A
Bioorg Med Chem
. 2001 Apr;
9(3):763-72.
PMID: 11310611
Cyclic 12-, 13- and 14-membered ring angiotensin II analogues related to disulfides but encompassing methylene-dithioether bridges have been prepared. The affinity data from these derivatives were compared to those from...
14.
Larhed M, Hallberg A
Drug Discov Today
. 2001 Apr;
6(8):406-416.
PMID: 11301285
In both lead identification and lead optimization processes there is an acute need for new organic small molecules. Traditional methods of organic synthesis are orders of magnitude too slow to...
15.
Alterman M, Sjobom H, Safsten P, Markgren P, Danielson U, Hamalainen M, et al.
Eur J Pharm Sci
. 2001 Apr;
13(2):203-12.
PMID: 11297905
The commonly used HIV-1 protease assays rely on measurements of the effect of inhibitions on the hydrolysis rate of synthetic peptides. Recently an assay based on surface plasmon resonance (SPR)...
16.
Johansson A, Hubatsch I, AKERBLOM E, Lindeberg G, Winiwarter S, Danielson U, et al.
Bioorg Med Chem Lett
. 2001 Feb;
11(2):203-6.
PMID: 11206459
Structure activity relationships (SARs) of product-based inhibitors of hepatitis C virus NS3 protease were evaluated using an in vitro assay system comprising the native bifunctional full-length NS3 (protease-helicase/NTPase). The results...
17.
Schaal W, Karlsson A, Ahlsen G, Lindberg J, Andersson H, Danielson U, et al.
J Med Chem
. 2001 Feb;
44(2):155-69.
PMID: 11170625
We have previously reported on the unexpected flipped conformation in the cyclic sulfamide class of inhibitors. An attempt to induce a symmetric binding conformation by introducing P2/P2' substituents foreseen to...
18.
Ahveninen J, Jaaskelainen I, Pekkonen E, Hallberg A, Hietanen M, Naatanen R, et al.
Alcohol Clin Exp Res
. 2001 Jan;
24(12):1850-4.
PMID: 11141044
Background: Chronic alcoholism is accompanied by "frontal" neuropsychological deficits that include an inability to maintain focus of attention. This might be associated with pronounced involuntary attention shifting to task-irrelevant stimulus...
19.
Hamalainen M, Markgren P, Schaal W, Karlen A, Classon B, Vrang L, et al.
J Biomol Screen
. 2000 Nov;
5(5):353-60.
PMID: 11080694
The interaction between 290 structurally diverse human immunodeficiency virus type 1 (HIV-1) protease inhibitors and the immobilized enzyme was analyzed with an optical biosensor. Although only a single concentration of...
20.
Marelius J, Ohlsson S, Persson A, Swedberg G, Andersson P, Andersson S, et al.
J Med Chem
. 2000 Oct;
43(21):3852-61.
PMID: 11052790
The relative binding affinities to human dihydrofolate reductase of four new potential antifolates, containing ester linkages between the two aromatic systems, were estimated by free energy perturbation simulations. The ester...