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A Hallberg

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Articles 93
Citations 921
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Recent Articles
21.
Johansson A, AKERBLOM E, Ersmark K, Lindeberg G, Hallberg A
J Comb Chem . 2000 Oct; 2(5):496-507. PMID: 11029175
A method for solid-phase peptide synthesis in the N- to C-direction that delivers good coupling yields and a low degree of epimerization is reported. The optimized method involves the coupling,...
22.
Lindman S, Lindeberg G, Nyberg F, Karlen A, Hallberg A
Bioorg Med Chem . 2000 Oct; 8(9):2375-83. PMID: 11026551
Rigidification of peptides by cyclization and iterative incorporation of well-defined secondary structure mimetics constitutes one approach to the design of non-peptidergic structures with better defined conformations. We herein present the...
23.
Lindstrom S, Ripa L, Hallberg A
Org Lett . 2000 Aug; 2(15):2291-3. PMID: 10930266
The anabasine analogues spiro[4-azaindan-1,2'-piperidine] (7) and spiro[6-azaindan-1,2'-piperidine] (8) have been prepared. A series of palladium-catalyzed reactions, where an intramolecular cyclization constituted a key reaction, were utilized for the preparation of...
24.
Ahveninen J, Jaaskelainen I, Pekkonen E, Hallberg A, Hietanen M, Naatanen R, et al.
Neurosci Lett . 2000 May; 285(2):131-4. PMID: 10793244
First weeks after alcohol withdrawal, associated with profound changes in neural transmission, constitute the critical period for relapse prevention and pharmacological intervention in alcoholism. Here, 20 male alcoholics with 1-6...
25.
Johannesson P, Lindeberg G, Tong W, Gogoll A, Synnergren B, Nyberg F, et al.
J Med Chem . 1999 Dec; 42(22):4524-37. PMID: 10579816
A simple experimental procedure on solid phase for the construction of new tripeptidic 5,9- and 5,10-fused thiazabicycloalkane scaffolds that adopt beta-turns has been developed. This N-terminal-directed bicyclization, relying on masked...
26.
HULTEN J, Andersson H, Schaal W, Danielson H, Classon B, Kvarnstrom I, et al.
J Med Chem . 1999 Oct; 42(20):4054-61. PMID: 10514275
Symmetric cyclic sulfamides, substituted in the P2/P2' position with functional groups foreseen to bind preferentially to the S2/S2' subsites of HIV-1 protease, have been prepared. Despite efforts to promote a...
27.
Ahveninen J, Jaaskelainen I, Pekkonen E, Hallberg A, Hietanen M, Makela R, et al.
Alcohol Clin Exp Res . 1999 Oct; 23(9):1507-14. PMID: 10512317
Background: Pronounced disruption of memory traces by subsequent distractors may result in impaired behavioral memory performance in alcoholics. Methods: This hypothesis was investigated with an electrophysiological index of auditory sensory-memory...
28.
Alterman M, Andersson H, Garg N, Ahlsen G, Lovgren S, Classon B, et al.
J Med Chem . 1999 Oct; 42(19):3835-44. PMID: 10508432
An analysis of the X-ray structure of a complex of HIV-1 protease with a linear C(2)-symmetric C-terminal duplicated inhibitor guided the selection of a series of diverse target compounds. These...
29.
Ahveninen J, Jaaskelainen I, Pekkonen E, Hallberg A, Hietanen M, Naatanen R, et al.
Neurosci Lett . 1999 Jul; 268(2):57-60. PMID: 10400077
We investigated the effects of chronic alcoholism on middle-latency auditory evoked potentials (MAEP) in 14 male alcoholics with 1-6 weeks of abstinence (without other severe disorders) and 13 age-matched male...
30.
Johannesson P, Lindeberg G, Tong W, Gogoll A, Karlen A, Hallberg A
J Med Chem . 1999 Mar; 42(4):601-8. PMID: 10052967
Analogues of the hypertensive octapeptide angiotensin II, comprising novel constrained 5,8-bicyclic and 5,9-bicyclic tripeptide units adopting nonclassical beta-turn geometries, as deduced from theoretical conformational analysis, have been synthesized. Spontanous bicyclization...