A D Riggs
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Explore the profile of A D Riggs including associated specialties, affiliations and a list of published articles.
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Articles
129
Citations
5651
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Recent Articles
1.
Pfeifer G, Riggs A
Methods Mol Biol
. 2011 Mar;
15:153-68.
PMID: 21400273
Chromatin structure analysis at single-nucleotide resolution can be done by genomic sequencing, and, recently, several techniques have been developed (1) that give improved specificity and sensitivity over the original method...
2.
PAP-LMPCR for improved, allele-specific footprinting and automated chromatin fine structure analysis
Ingram R, Gao C, Lebon J, Liu Q, Mayoral R, Sommer S, et al.
Nucleic Acids Res
. 2008 Jan;
36(3):e19.
PMID: 18208840
The analysis of chromatin fine structure and transcription factor occupancy of differentially expressed genes by in vivo footprinting and ligation-mediated-PCR (LMPCR) is a powerful tool to understand the impact of...
3.
Omori K, Valiente L, Orr C, Rawson J, Ferreri K, Todorov I, et al.
Transplant Proc
. 2005 Nov;
37(8):3422-3.
PMID: 16298615
The development of an optimal islet cryopreservation method will permit transplantation of islets from multiple donors in a single procedure and contribute to alleviation of the islet shortage. In this...
4.
Rodin S, Parkhomchuk D, Riggs A
Biochemistry (Mosc)
. 2005 Jun;
70(5):559-67.
PMID: 15948709
Consideration of epigenetic silencing, perhaps by DNA methylation, led to an epigenetic complementation (EC) model for evolution by gene duplication (Rodin and Riggs (2003) J. Mol. Evol., 56, 718-729). This...
5.
Riggs A
Cytogenet Genome Res
. 2003 Aug;
99(1-4):17-24.
PMID: 12900540
X chromosome inactivation and DNA methylation are reviewed, with emphasis on the contributions of Susumu Ohno and the predictions made in my 1975 paper (Riggs, 1975), in which I proposed...
6.
Shively L, Chang L, LeBon J, Liu Q, Riggs A, Singer-Sam J
Biotechniques
. 2003 Apr;
34(3):498-502, 504.
PMID: 12669699
We describe here a quantitative real-time PCR assay for the detection of single-base-pair differences that does not require fluorescently labeled gene-specific probes or complicated primer combinations. Following PCR or RT-PCR...
7.
Dai S, OConnor T, Holmquist G, Riggs A, Flanagan S
Biotechniques
. 2002 Nov;
33(5):1090-7.
PMID: 12449387
The investigation of in vivo DNA repair in mammalian cells at nucleotide resolution requires the quantification of break frequencies less than one per kilobase. By optimizing several parameters of the...
8.
9.
Chen H, Kontaraki J, Bonifer C, Riggs A
Sci STKE
. 2001 Dec;
2001(77):pl1.
PMID: 11752648
Terminal transferase-dependent PCR (TDPCR) is a versatile, sensitive method for detecting DNA lesions such as those generated by the footprinting agents commonly used to detect in vivo protein-DNA interactions. Data...
10.
Scherr M, Lebon J, Castanotto D, Cunliffe H, Meltzer P, Ganser A, et al.
Mol Ther
. 2001 Nov;
4(5):454-60.
PMID: 11708882
The efficacies of antisense oligonucleotides and ribozymes are greatly dependent on the accessibility of their mRNA targets. Target site accessibility is affected by both RNA structure and the proteins associated...