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J E Shively

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Articles 283
Citations 3635
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Recent Articles
1.
Ma X, Meng Z, Jin L, Xiao Z, Wang X, Tsark W, et al.
Oncogene . 2017 Mar; 36(28):4060-4071. PMID: 28319059
Inflammation is one of the major risk factors for cancer. Here, we show that calcium/calmodulin-dependent protein kinase II gamma (CAMK2γ) in intestinal epithelial cells (IECs) modulates inflammatory signals and promotes...
2.
Yokoyama S, Chen C, Nguyen T, Shively J
Oncogene . 2007 Jun; 26(55):7637-46. PMID: 17546042
CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1) is a type I transmembrane glycoprotein expressed in epithelial cells with three or four extracellular domains (ECDs) and either long or short cytoplasmic...
3.
Bjerner J, Lebedin Y, Bellanger L, Kuroki M, Shively J, Varaas T, et al.
Tumour Biol . 2002 Dec; 23(4):249-62. PMID: 12499780
To characterize antigenic sites in carcinoembryonic antigen (CEA) further and to investigate whether there are differences between colon tumor CEA and meconium CEA (NCA-2) that can be detected by anti-CEA...
4.
Stratton L, Kelly R, Rowe J, Shively J, Smith D, Carpenter J, et al.
J Pharm Sci . 2001 Dec; 90(12):2141-8. PMID: 11745773
The rate of deamidation of the Asn residue in Val-Tyr-Pro-Asn-Gly-Ala (VYPNGA), a model peptide, was determined at pH 9 (400 mM Tris buffer) as a function of temperature and peptide...
5.
Schumann D, Chen C, Kaplan B, Shively J
J Biol Chem . 2001 Oct; 276(50):47421-33. PMID: 11595750
CEA cell adhesion molecule 1 (CEACAM1), a type 1 transmembrane and homotypic cell adhesion protein belonging to the carcinoembryonic antigen (CEA) gene family and expressed on epithelial cells, is alternatively...
6.
Beauchemin N, Draber P, Dveksler G, Gold P, Grunert F, Hammarstrom S, et al.
Exp Cell Res . 2001 Aug; 252(2):243-9. PMID: 11501563
No abstract available.
7.
Keire D, Jang Y, Li L, Dasgupta S, Goddard 3rd W, Shively J
Inorg Chem . 2001 Aug; 40(17):4310-8. PMID: 11487337
This work describes the modification of the chelating agent 1,4,7,10-tetraazacyclododecane-N,N',N' ',N' "-tetraacetic acid (DOTA) to improve the rate of metal loading for radioimmunotherapy applications. Previous ab initio calculations predicted that...
8.
Williams L, Beatty B, Shively J, Beatty J
Cancer Biother Radiopharm . 2001 Jun; 16(2):147-57. PMID: 11385961
A comparison was made between labeled antibody accumulations in nude mice having either single or multiple human xenografts. The LS174T tumors were implanted subcutaneously. All animals were given 2 micrograms...
9.
Yazaki P, Shively L, Clark C, Cheung C, Le W, Szpikowska B, et al.
J Immunol Methods . 2001 Jun; 253(1-2):195-208. PMID: 11384681
Genetically engineered radiolabeled antibody fragments have shown great promise for the radioimmunoscintigraphy of cancer. Retaining the exquisite specificity of monoclonal antibodies yet smaller in molecular size, antibody fragments display rapid...
10.
Hoffmann P, Mueller N, Shively J, Fleischer B, Neumaier M
Int J Cancer . 2001 May; 92(5):725-32. PMID: 11340579
Genetic engineering can be used to generate antigen-specific molecules for improved tumor immunotherapy. We have constructed genes coding for fusion proteins consisting of a high-affinity antibody single-chain antibody fragment (scFv)...