High-performance Web Services for Querying Gene and Variant Annotation

Overview

Journal Genome Biol

Specialties Biology
Genetics

Date 2016 May 8

PMID 27154141

Citations 110

Authors

Jiwen Xin

Adam Mark

Cyrus Afrasiabi

Ginger Tsueng

Moritz Juchler

Nikhil Gopal

Gregory S Stupp

Timothy E Putman

Benjamin J Ainscough

Obi L Griffith

Ali Torkamani

Patricia L Whetzel

Christopher J Mungall

Sean D Mooney

Andrew I Su

Chunlei Wu

Affiliations

Soon will be listed here.

Abstract

Efficient tools for data management and integration are essential for many aspects of high-throughput biology. In particular, annotations of genes and human genetic variants are commonly used but highly fragmented across many resources. Here, we describe MyGene.info and MyVariant.info, high-performance web services for querying gene and variant annotation information. These web services are currently accessed more than three million times permonth. They also demonstrate a generalizable cloud-based model for organizing and querying biological annotation information. MyGene.info and MyVariant.info are provided as high-performance web services, accessible at http://mygene.info and http://myvariant.info . Both are offered free of charge to the research community.

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