Validity of Non-invasive Point-of-care Hemoglobin Estimation in Healthy and Sick Children-a Method Comparison Study

Overview

Journal Eur J Pediatr

Specialty Pediatrics

Date 2015 Aug 20

PMID 26286814

Citations 7

Authors

Aditya Bhat

Amit Upadhyay

Vijay Jaiswal

Deepak Chawla

Dharamveer Singh

Mithilesh Kumar

C P Yadav

Affiliations

Soon will be listed here.

Abstract

Conclusions: SpHb showed good accuracy and correlated well with lab estimated Hb levels in healthy children. However, in children with impaired peripheral perfusion, its diagnostic accuracy was inadequate to justify routine use for quantification of severity of anemia and making transfusion decisions solely on non-invasive estimation of hemoglobin.

What Is Known: Non-invasive hemoglobin estimation is a relatively new and novel method which has given mixed results regarding its potential efficacy in adults. There is limited data regarding usefulness and accuracy of non-invasive Hb estimation by SpHb in sick neonates and children.

What Is New: Non-invasive Hb estimation by SpHb monitor is reasonably accurate in healthy neonates and children. It can be used in critically ill children and neonates, but in conjunction with lab confirmation of Hb values.

Citing Articles

Accuracy of continuous and real-time total hemoglobin during bimaxillary orthognathic surgery.

Kim C, Yoon J, Yun G, Kim H, Kim E J Dent Anesth Pain Med. 2025; 25(1):23-32.

PMID: 39944844 PMC: 11811515. DOI: 10.17245/jdapm.2025.25.1.23.

Validation of ToucHb, a non-invasive haemoglobin estimation: Effective for normal ranges, needs improvement for anaemia detection.

Channa Basappa Y, Majgi S, Shashidhar S, Srinivas P PLOS Glob Public Health. 2024; 4(3):e0001541.

PMID: 38470938 PMC: 10931486. DOI: 10.1371/journal.pgph.0001541.

Evaluation of the use of non-invasive hemoglobin measurement in early childhood.

Arai Y, Shoji H, Awata K, Inage E, Ikuse T, Shimizu T Pediatr Res. 2022; 93(4):1036-1040.

PMID: 35906313 DOI: 10.1038/s41390-022-02204-7.

Reliability of transcutaneous hemoglobin measurements in an outpatient pediatric clinic.

Margulies S, Posa M, FitzGerald M, Filipp S, Howell D, Tung P Postgrad Med. 2021; 134(2):200-204.

PMID: 34895027 PMC: 8983555. DOI: 10.1080/00325481.2021.2018256.

Intraoperative continuous noninvasive hemoglobin monitoring in patients with placenta previa undergoing cesarean section: a prospective observational study.

Kim H, Do S, Hwang J, Na H Anesth Pain Med (Seoul). 2020; 14(4):423-428.

PMID: 33329772 PMC: 7713795. DOI: 10.17085/apm.2019.14.4.423.

References

Kotecha P . Nutritional anemia in young children with focus on Asia and India. Indian J Community Med. 2011; 36(1):8-16. PMC: 3104701. DOI: 10.4103/0970-0218.80786. View

Shah N, Osea E, Martinez G . Accuracy of noninvasive hemoglobin and invasive point-of-care hemoglobin testing compared with a laboratory analyzer. Int J Lab Hematol. 2013; 36(1):56-61. PMC: 4232003. DOI: 10.1111/ijlh.12118. View

Gayat E, Aulagnier J, Matthieu E, Boisson M, Fischler M . Non-invasive measurement of hemoglobin: assessment of two different point-of-care technologies. PLoS One. 2012; 7(1):e30065. PMC: 3253126. DOI: 10.1371/journal.pone.0030065. View

Gayat E, Bodin A, Sportiello C, Boisson M, Dreyfus J, Mathieu E . Performance evaluation of a noninvasive hemoglobin monitoring device. Ann Emerg Med. 2011; 57(4):330-3. DOI: 10.1016/j.annemergmed.2010.11.032. View

Awada W, Mohmoued M, Radwan T, Hussien G, Elkady H . Continuous and noninvasive hemoglobin monitoring reduces red blood cell transfusion during neurosurgery: a prospective cohort study. J Clin Monit Comput. 2015; 29(6):733-40. PMC: 4621711. DOI: 10.1007/s10877-015-9660-4. View

Istaphanous G, Wheeler D, Lisco S, Shander A . Red blood cell transfusion in critically ill children: a narrative review. Pediatr Crit Care Med. 2010; 12(2):174-83. DOI: 10.1097/PCC.0b013e3181e30d09. View

Berkow L, Rotolo S, Mirski E . Continuous noninvasive hemoglobin monitoring during complex spine surgery. Anesth Analg. 2011; 113(6):1396-402. DOI: 10.1213/ANE.0b013e318230b425. View

Nguyen B, Vincent J, Nowak E, Coat M, Paleiron N, Gouny P . The accuracy of noninvasive hemoglobin measurement by multiwavelength pulse oximetry after cardiac surgery. Anesth Analg. 2011; 113(5):1052-7. DOI: 10.1213/ANE.0b013e31822c9679. View

Colquhoun D, Forkin K, Durieux M, Thiele R . Ability of the Masimo pulse CO-Oximeter to detect changes in hemoglobin. J Clin Monit Comput. 2012; 26(2):69-73. DOI: 10.1007/s10877-012-9335-3. View

10.

Lamhaut L, Apriotesei R, Combes X, Lejay M, Carli P, Vivien B . Comparison of the accuracy of noninvasive hemoglobin monitoring by spectrophotometry (SpHb) and HemoCue® with automated laboratory hemoglobin measurement. Anesthesiology. 2011; 115(3):548-54. DOI: 10.1097/ALN.0b013e3182270c22. View

11.

. Recommendations for reference method for haemoglobinometry in human blood (ICSH standard 1986) and specifications for international haemiglobincyanide reference preparation (3rd edition). International Committee for Standardization in Haematology;.... Clin Lab Haematol. 1987; 9(1):73-9. DOI: 10.1111/j.1365-2257.1987.tb01384.x. View

12.

Applegate 2nd R, Barr S, Collier C, Rook J, Mangus D, Allard M . Evaluation of pulse cooximetry in patients undergoing abdominal or pelvic surgery. Anesthesiology. 2011; 116(1):65-72. DOI: 10.1097/ALN.0b013e31823d774f. View

13.

Rice M, Gravenstein N, Morey T . Noninvasive hemoglobin monitoring: how accurate is enough?. Anesth Analg. 2013; 117(4):902-907. DOI: 10.1213/ANE.0b013e31829483fb. View

14.

Causey M, Miller S, Foster A, Beekley A, Zenger D, Martin M . Validation of noninvasive hemoglobin measurements using the Masimo Radical-7 SpHb Station. Am J Surg. 2011; 201(5):592-8. DOI: 10.1016/j.amjsurg.2011.01.020. View

15.

Goldstein B, Giroir B, Randolph A . International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med. 2005; 6(1):2-8. DOI: 10.1097/01.PCC.0000149131.72248.E6. View

16.

Jung Y, Lee J, Kim H, Shin S, Sohn J, Kim E . The efficacy of noninvasive hemoglobin measurement by pulse CO-oximetry in neonates. Pediatr Crit Care Med. 2012; 14(1):70-3. DOI: 10.1097/PCC.0b013e318260117d. View

17.

Butwick A, Hilton G, Carvalho B . Non-invasive haemoglobin measurement in patients undergoing elective Caesarean section. Br J Anaesth. 2011; 108(2):271-7. DOI: 10.1093/bja/aer373. View

18.

Miller R, Ward T, Shiboski S, Cohen N . A comparison of three methods of hemoglobin monitoring in patients undergoing spine surgery. Anesth Analg. 2011; 112(4):858-63. DOI: 10.1213/ANE.0b013e31820eecd1. View

19.

von Schweinitz B, De Lorenzo R, Cuenca P, Anschutz R, Allen P . Does a non-invasive hemoglobin monitor correlate with a venous blood sample in the acutely ill?. Intern Emerg Med. 2014; 10(1):55-61. DOI: 10.1007/s11739-014-1129-9. View

20.

Macknet M, Allard M, Applegate 2nd R, Rook J . The accuracy of noninvasive and continuous total hemoglobin measurement by pulse CO-Oximetry in human subjects undergoing hemodilution. Anesth Analg. 2010; 111(6):1424-6. DOI: 10.1213/ANE.0b013e3181fc74b9. View