Recent Advances in the CRANK Software Suite for Experimental Phasing

Overview

Journal Acta Crystallogr D Biol Crystallogr

Specialty Chemistry

Date 2011 Apr 5

PMID 21460451

Citations 56

Authors

Navraj S Pannu

Willem Jan Waterreus

Pavol Skubak

Irakli Sikharulidze

Jan Pieter Abrahams

Rudolf A G de Graaff

Affiliations

Soon will be listed here.

Abstract

For its first release in 2004, CRANK was shown to effectively detect and phase anomalous scatterers from single-wavelength anomalous diffraction data. Since then, CRANK has been significantly improved and many more structures can be built automatically with single- or multiple-wavelength anomalous diffraction or single isomorphous replacement with anomalous scattering data. Here, the new algorithms that have been developed that have led to these substantial improvements are discussed and CRANK's performance on over 100 real data sets is shown. The latest version of CRANK is freely available for download at http://www.bfsc.leidenuniv.nl/software/crank/ and from CCP4 (http://www.ccp4.ac.uk/).

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