Organic Process Research & Development
Overview
Organic Process Research & Development is a peer-reviewed scientific journal that focuses on the development and optimization of organic chemical processes. It covers a wide range of topics including reaction design, catalyst development, process scale-up, and green chemistry. The journal provides a platform for researchers and industrial practitioners to share their innovative approaches and advancements in the field of organic process research and development.
Details
Details
Abbr.
Org Process Res Dev
Publisher
American Chemical Society
Start
1997
End
Continuing
Frequency
Bimonthly
p-ISSN
1083-6160
e-ISSN
1520-586X
Country
United States
Language
English
Metrics
Metrics
h-index / Ranks: 2024
127
SJR / Ranks: 4485
900
CiteScore / Ranks: 3323
6.50
JIF / Ranks: 2884
3.4
Recent Articles
21.
Zhou Z, Kasten K, Kang T, Cordes D, Smith A
Org Process Res Dev
. 2024 May;
28(5):2041-2049.
PMID: 38783855
A packed reactor bed incorporating a polymer-supported isothiourea HyperBTM catalyst derivative has been used to promote the enantioselective synthesis of a range of heterocyclic products derived from α-azol-2-ylacetophenones and -acetamides...
22.
Daglish J, Blacker A, de Boer G, Russell S, Tausif M, Hose D, et al.
Org Process Res Dev
. 2024 May;
28(5):1979-1989.
PMID: 38783854
Presented here is the design and performance of a coalescing liquid-liquid filter, based on low-cost and readily available meltblown nonwoven substrates for separation of immiscible phases. The performance of the...
23.
Edwards M, Pratley M, Gordon C, Teixeira R, Ali H, Mahmood I, et al.
Org Process Res Dev
. 2024 May;
28(5):1917-1928.
PMID: 38783853
We describe the optimization and scale-up of two consecutive reaction steps in the synthesis of bio-derived alkoxybutenolide monomers that have been reported as potential replacements for acrylate-based coatings (Sci. Adv.2020,...
24.
Bonner A, Baumann M
Org Process Res Dev
. 2024 May;
28(5):1567-1575.
PMID: 38783852
A new and highly efficient continuous flow process is presented for the synthesis of aziridines via the thermal Baldwin rearrangement. The process was initially explored using traditional batch synthesis techniques...
25.
Ryan M, Lynch D, Collins S, Maguire A
Org Process Res Dev
. 2024 May;
28(5):1946-1963.
PMID: 38783851
Thermal -Boc deprotection of a range of amines is readily effected in continuous flow, in the absence of an acid catalyst. While the optimum results were obtained in methanol or...
26.
Gnadinger U, Poier D, Trombini C, Dabros M, Marti R
Org Process Res Dev
. 2024 May;
28(5):1860-1868.
PMID: 38783850
The use of sustainable oxidants is of great interest to the chemical industry, considering the importance of oxidation reactions for the manufacturing of chemicals and society's growing awareness of its...
27.
Wang J, Erdem E, Woodley J
Org Process Res Dev
. 2024 May;
27(6):1111-1121.
PMID: 38779303
Biocatalytic oxidation is an interesting prospect for the selective synthesis of active pharmaceutical intermediates. Bubbling air or oxygen is considered as an efficient method to increase the gas-liquid interface and...
28.
Bento C, Katz M, Santos M, Afonso C
Org Process Res Dev
. 2024 Apr;
28(4):860-890.
PMID: 38660381
Poly(ethylene glycol) (PEG) is the polymer of choice in drug delivery systems due to its biocompatibility and hydrophilicity. For over 20 years, this polymer has been widely used in the...
29.
Kalmode H, Ravikumar O, Paymode D, Bachert J, Burns J, Stringham R, et al.
Org Process Res Dev
. 2024 Apr;
28(4):1195-1204.
PMID: 38660380
Sutezolid is an in-development thiomorpholine derivative of the FDA-approved tuberculosis (TB) treatment linezolid. Current synthetic routes for preparing sutezolid start with thiomorpholine as a key structural building block; unfortunately, this...
30.
Xiao H, Feng Y, Goundry W, Karlsson S
Org Process Res Dev
. 2024 Apr;
28(4):891-923.
PMID: 38660379
Separation and purification in organic solvents are indispensable procedures in pharmaceutical manufacturing. However, they still heavily rely on the conventional separation technologies of distillation and chromatography, resulting in high energy...