Organic Process Research & Development
Overview
Organic Process Research & Development is a peer-reviewed scientific journal that focuses on the development and optimization of organic chemical processes. It covers a wide range of topics including reaction design, catalyst development, process scale-up, and green chemistry. The journal provides a platform for researchers and industrial practitioners to share their innovative approaches and advancements in the field of organic process research and development.
Details
Details
Abbr.
Org Process Res Dev
Publisher
American Chemical Society
Start
1997
End
Continuing
Frequency
Bimonthly
p-ISSN
1083-6160
e-ISSN
1520-586X
Country
United States
Language
English
Metrics
Metrics
h-index / Ranks: 2024
127
SJR / Ranks: 4485
900
CiteScore / Ranks: 3323
6.50
JIF / Ranks: 2884
3.4
Recent Articles
11.
Prenzel T, Schwarz N, Hammes J, Krahe F, Pschierer S, Winter J, et al.
Org Process Res Dev
. 2024 Oct;
28(10):3922-3928.
PMID: 39444427
1-1-Hydroxyquinolin-4-ones represent a broad class of biologically active heterocycles having an exocyclic N,O motif. Electrosynthesis offers direct, highly selective, and sustainable access to 1-hydroxyquinol-4-ones by nitro reduction. A versatile synthetic...
12.
Jones V, Bennett G, Bennett C
Org Process Res Dev
. 2024 Oct;
28(7):2819-2826.
PMID: 39372330
The development of a continuous flow reactor for stereospecific glycosylation reactions with deoxy sugars is described. This apparatus that permits optimizing the selectivity of glycosylation reactions based on the stability...
13.
Ali H, Ahmed I, Robertson K, Lanterna A
Org Process Res Dev
. 2024 Sep;
28(9):3698-3706.
PMID: 39323896
Perylene diimides (PDI) have an extraordinary ability to activate both energy and electron transfer processes upon light excitation; however, their extremely low solubility has hindered their wide use as photocatalysts....
14.
Fyfe C, Barrington H, Gordon C, Reid M
Org Process Res Dev
. 2024 Sep;
28(9):3661-3673.
PMID: 39323895
Mixing is one of the most important nonchemical considerations in the design of scalable processes. While noninvasive imaging approaches to deliver a quantifiable understanding of mixing dynamics are well-known, the...
15.
Guthrie D, Saathoff J, Sahani R, Nunes De Souza A, Cook D, Hochstetler S, et al.
Org Process Res Dev
. 2024 Aug;
28(8):3197-3205.
PMID: 39171130
Herein, we describe two practical approaches to synthesize ()-(+)-1,2-epoxy-5-hexene from inexpensive and readily available raw materials and reagents. The first approach is a two-step sequence, involving an epoxidation with -chloroperoxybenzoic...
16.
Bannon R, Morrison G, Smyth M, Moody T, Wharry S, Roth P, et al.
Org Process Res Dev
. 2024 Aug;
28(8):3307-3312.
PMID: 39171129
A continuous flow approach for the aerobic photo-oxidation of benzylic substrates to ketone and aldehyde products is presented. The resulting process exploits UV-A LEDs (375 nm) in combination with a...
17.
Pal S, Pankajakshan A, Besenhard M, Snead N, Almeida J, Abukhamees S, et al.
Org Process Res Dev
. 2024 Jul;
28(7):2755-2764.
PMID: 39055968
The fourth industrial revolution is gaining momentum in the pharmaceutical industry. However, particulate processes and suspension handling remain big challenges for automation and the implementation of real-time particle size analysis....
18.
Naik P, Garcia-Lacuna J, ONeill P, Baumann M
Org Process Res Dev
. 2024 May;
28(5):1587-1596.
PMID: 38783858
A simple and benign continuous flow oxidation protocol for the selective conversion of primary and secondary alcohols into their respective aldehyde and ketone products is reported. This approach makes use...
19.
Bennett J, Murphy P
Org Process Res Dev
. 2024 May;
28(5):1848-1859.
PMID: 38783857
C-Glycosyl compounds (C-glycosides) are a class of saccharide derivatives with improved stability over their O-linked counterparts. This paper reports the synthesis of several -2-(C-glycosyl)acetates via a tandem Wittig-Michael reaction from...
20.
Martina K, Moran M, Manzoli M, Trukhan M, Kuhn S, Van Gerven T, et al.
Org Process Res Dev
. 2024 May;
28(5):1515-1528.
PMID: 38783856
A robust supported catalyst that is made up of copper nanoparticles on Celite has been successfully prepared for the selective transfer hydrogenation of aromatic nitrobenzenes to anilines under continuous flow....