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Cancer Clinical Trials

Cancer Clinical Trials is a scientific journal, published since 1978 in English. The journal's country of origin is United States and its primary focus areas are oncology and pharmacology.

Details
Abbr. Cancer Clin Trials
Start 1978
End 1981
Frequency Quarterly
p-ISSN 0190-1206
Country United States
Language English
Specialties Oncology
Pharmacology
Recent Articles
1.
Andrews J
Cancer Clin Trials . 1981 Jan; 4(4):483-95. PMID: 7318131
Two methods dominate cancer treatment--one, the traditional best practice, individualized treatment method and two, the a priori determined decision method of the interinstitutional, cooperative, clinical trial. In the first, choices...
2.
Potish R, Boen J, LEVITT S
Cancer Clin Trials . 1981 Jan; 4(4):475-81. PMID: 7318130
A recent report in the literature was unable to associate the local--regional recurrence rates in breast cancer with deviations from the protocol's recommended dosages. The investigators proceeded to infer that...
3.
Karp G, Antman K, Canellos G
Cancer Clin Trials . 1981 Jan; 4(4):465-7. PMID: 7318129
Forty-six patients with various malignancies refractory to standard chemotherapy were treated with VP-16-213 using a weekly schedule. Only one patient responded to this regimen. perivenous infiltration of VP-16-213 resulted in...
4.
Bedikian A, Bodey G, Burgess M, Freireich E
Cancer Clin Trials . 1981 Jan; 4(4):459-63. PMID: 7318128
A phase I clinical study of aziridinylbenzoquinone (AZQ) was conducted in 33 patients with various types of advanced solid tumors to evaluate its toxicity and efficacy. The initial dose of...
5.
Lavin P
Cancer Clin Trials . 1981 Jan; 4(4):451-7. PMID: 7318127
To date, in cancer clinical trials, treatment programs have been evaluated using objective tumor response as the primary means to demonstrate antitumor activity. This measure, which is based upon a...
6.
Schauer P, Wittes R, Gralla R, Casper E, Young C
Cancer Clin Trials . 1981 Jan; 4(4):433-7. PMID: 7318126
4'-epi-adriamycin was administered intravenously on an every-3-week schedule to 34 patients with advanced malignant tumors. Patients were treated at five dosage levels, ranging from 40 mg/m2 to 100 mg/m2. Hematologic...
7.
Kelsen D, Ribaud P, ALCOCK N, Burchenal J, Young C, MATHE G
Cancer Clin Trials . 1981 Jan; 4(4):429-31. PMID: 7318125
Malonato-(1,2 diaminocyclohexane) platinum (MP) is a new platinum analog currently undergoing phase I clinical trials. Using flameless atomic absorption spectrophotometry, the pharmacokinetics of MP were studied at five dosage levels....
8.
Helson L, Traganos F, Miller D
Cancer Clin Trials . 1981 Jan; 4(4):415-21. PMID: 7318124
Using flow cytometric analysis, we followed changes in a patient's bone marrow which was infiltrated with cells resistant to chemotherapy. Samples taken prior to, during, and after treatment with dianhydrogalactitol...
9.
Fuks J, Van Echo D, Aisner J, Mitchell E, WOOLLEY 3rd P, Wiernik P
Cancer Clin Trials . 1981 Jan; 4(4):411-4. PMID: 7318123
Fourteen patients with metastatic renal cell carcinoma received methyl-G weekly at a starting dose of 600 mg/m2 (five patients) and 500 mg/m2 (nine patients) intravenously. All 14 patients are evaluable...
10.
Mischler N, Tormey D, Klotz J, Borden E, Ramirez G, Banerjee T, et al.
Cancer Clin Trials . 1981 Jan; 4(4):407-10. PMID: 7318122
In a phase II study dibromodulcitol (DBD), an alpha-omega dibrominated hexitol, was used to treat 99 previously treated patients with colon, rectal, kidney, and other tumors. Six patients were ineligible...