Zuoquan Zhao
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Explore the profile of Zuoquan Zhao including associated specialties, affiliations and a list of published articles.
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22
Citations
96
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Recent Articles
1.
Liang Y, Wang X, Chen Y, Zeng X, Liu J, Zhao Z, et al.
Mol Pharm
. 2024 Sep;
21(10):4960-4969.
PMID: 39279392
The limited progress in treatment options and the alarming survival rates in advanced melanoma emphasize the significant research importance of early melanoma diagnosis. RFVT3, a crucial protein at the core...
2.
Zhang G, Zhao S, Zhao Z, Jia C, Zhang Y, Xue J, et al.
ACS Chem Neurosci
. 2024 Sep;
15(19):3459-3472.
PMID: 39276340
The dopamine D3 receptor (D3R) is important in the pathophysiology of various neuropsychiatric disorders, such as depression, bipolar disorder, schizophrenia, drug addiction, and Parkinson's disease. Positron emission tomography (PET) with...
3.
Peng S, Liang Y, Zhu H, Wang Y, Li Y, Zhao Z, et al.
Redox Biol
. 2024 Aug;
75:103294.
PMID: 39096854
Idiopathic pulmonary fibrosis (IPF) is a serious interstitial lung disease. However, the definitive diagnosis of IPF is impeded by the limited capabilities of current diagnostic methods, which may fail to...
4.
Fan M, Yao J, Zhao Z, Zhang X, Lu J
Pharmaceuticals (Basel)
. 2024 Jul;
17(7).
PMID: 39065756
With the development of PD-1/PD-L1 immune checkpoint inhibitor therapy, the ability to monitor PD-L1 expression in the tumor microenvironment is important for guiding therapy. This study was performed to develop...
5.
Chen X, Xia D, Zeng X, Meng L, Wang Y, Li H, et al.
J Med Chem
. 2024 May;
67(10):8361-8371.
PMID: 38726551
Due to the complex heterogeneity in different cancer types, the heterodimeric strategy has been intensively practiced to improve the effectiveness of tumor diagnostics. In this study, we developed a series...
6.
Zhou H, Yao J, Zhao Z, Lu J
Chem Biol Drug Des
. 2023 Jun;
102(4):738-748.
PMID: 37328929
A series of benzylaminoimidazoline derivatives was synthesized and evaluated for norepinephrine transporter (NET) targeting. Among them, N-(3-iodobenzyl)-4,5-dihydro-1H-imidazol-2-amine (Compound 9) displayed the highest affinity for NET (IC = 5.65 ± 0.97 ...
7.
Zhao Z, Zhao Z, Zhang P
Sci Rep
. 2023 Jan;
13(1):578.
PMID: 36631559
Industrial agglomeration has attracted extensive attention from economists and geographers, yet it is still a challenge to identify the multi-agglomeration spatial structure and degree of industrial agglomeration in continuous space-there...
8.
Meng L, Fang J, Zhao L, Wang T, Yuan P, Zhao Z, et al.
J Med Chem
. 2022 Jun;
65(12):8245-8257.
PMID: 35658448
The fibroblast activation protein (FAP), overexpressed on cancer-associated fibroblasts (CAFs), has become a valuable target for tumor diagnosis and therapy. However, most FAP-based radioligands show insufficient tumor uptake and retention....
9.
Gu Y, Han K, Zhang Z, Zhao Z, Yan C, Wang L, et al.
J Nucl Cardiol
. 2022 Mar;
30(2):495-503.
PMID: 35322381
Background: Positron emission tomography (PET) imaging with radiolabeled fibroblasts activation protein inhibitor (FAPI) provides the opportunity to directly visualize fibrosis. This study aimed to investigate the feasibility of Ga-FAPI PET...
10.
Li X, Shi S, Zhou H, Zhao Z, Lu J
Mol Pharm
. 2021 Sep;
18(10):3811-3819.
PMID: 34519204
To develop novel norepinephrine transporter (NET)-targeting positron emission tomography (PET) probes with optimal pharmacokinetic properties, a series of -bromobenzylguanidine derivatives was synthesized. 4-Fluorodiethoxyethane-3-bromobenzylguanidine (compound ) showed relatively good affinity for...