Rongqiang Zhuang
Overview
Explore the profile of Rongqiang Zhuang including associated specialties, affiliations and a list of published articles.
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Articles
54
Citations
357
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Recent Articles
1.
Liu J, Liang Y, Yang H, Wang X, Zeng X, Zhuang R, et al.
J Med Chem
. 2024 Sep;
67(19):17690-17700.
PMID: 39305257
V-domain immunoglobulin suppressor of T cell activation (VISTA) plays a critical role in regulating innate and adaptive immune responses within the tumor immune microenvironment. Quantifying VISTA expression is necessary to...
2.
Liu H, Liu J, Chen Y, Yang H, Fang J, Zeng X, et al.
Eur J Nucl Med Mol Imaging
. 2024 Sep;
52(2):401-415.
PMID: 39289182
Purpose: The stimulator of interferon genes (STING) is a critical component of the innate immune system and plays a pivotal role in tumor immunotherapy. Developing non-invasive in vivo diagnostic methods...
3.
Peng S, Liang Y, Zhu H, Wang Y, Li Y, Zhao Z, et al.
Redox Biol
. 2024 Aug;
75:103294.
PMID: 39096854
Idiopathic pulmonary fibrosis (IPF) is a serious interstitial lung disease. However, the definitive diagnosis of IPF is impeded by the limited capabilities of current diagnostic methods, which may fail to...
4.
Feng L, Hu W, Zeng X, Wei Z, Long Y, Li M, et al.
Mol Pharm
. 2024 Jul;
21(9):4386-4394.
PMID: 39046432
This study aimed to evaluate a novel albumin-binding strategy for addressing the challenge of insufficient tumor retention of fibroblast activation protein inhibitors (FAPIs). Maleimide, a molecule capable of covalent binding...
5.
Zeng X, Liu H, Huang G, Wang Y, Zhou W, Wang Y, et al.
J Med Chem
. 2024 Jul;
67(15):13056-13066.
PMID: 39036887
Activation of the adenosine 2A receptor (AR) can lead to tumor immunosuppression, which results in poor prognosis of immunotherapy. The aim of this study was to design novel F-labeled probes...
6.
Fang J, Wang X, Meng L, Zhang J, Zhuang R, Li Y, et al.
ACS Pharmacol Transl Sci
. 2024 Jun;
7(6):1783-1794.
PMID: 38898942
The stimulator of interferon genes (STING) is a vital protein to the immune surveillance of the tumor microenvironment. In this study, we develop novel inhibitor-based radioligands and evaluate their feasibility...
7.
Chen X, Xia D, Zeng X, Meng L, Wang Y, Li H, et al.
J Med Chem
. 2024 May;
67(10):8361-8371.
PMID: 38726551
Due to the complex heterogeneity in different cancer types, the heterodimeric strategy has been intensively practiced to improve the effectiveness of tumor diagnostics. In this study, we developed a series...
8.
Li J, Li Y, Ming J, Zeng X, Wang T, Yang H, et al.
Angew Chem Int Ed Engl
. 2024 May;
63(30):e202401683.
PMID: 38719735
Lanthanide nanoparticle (LnNP) scintillators exhibit huge potential in achieving radionuclide-activated luminescence (radioluminescence, RL). However, their structure-activity relationship remains largely unexplored. Herein, progressive optimization of LnNP scintillators is presented to unveil...
9.
Meng L, Fang J, Zhang J, Li H, Xia D, Zhuang R, et al.
J Med Chem
. 2024 May;
67(10):8460-8472.
PMID: 38717104
Recognizing the significance of SPECT in nuclear medicine and the pivotal role of fibroblast activation protein (FAP) in cancer diagnosis and therapy, this study focuses on the development of Tc-labeled...
10.
Fang J, Zhang J, Meng L, Li H, Xia D, Wang Y, et al.
Mol Pharm
. 2024 Mar;
21(4):1942-1951.
PMID: 38447198
The stimulator of interferon genes (STING) is pivotal in mediating STING-dependent type I interferon production, which is crucial for enhancing tumor rejection. Visualizing STING within the tumor microenvironment is valuable...