Zoltan Takats
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Explore the profile of Zoltan Takats including associated specialties, affiliations and a list of published articles.
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191
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4727
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Recent Articles
1.
Ling S, Dexter A, Race A, Sharma S, Hamm G, Polanska U, et al.
Dis Model Mech
. 2025 Feb;
18(2).
PMID: 40019006
The PI3K-mTOR-AKT pathway regulates tumour proliferation, gene expression and metabolism, but pathway inhibition induces heterogeneous feedback reactivation, limiting anti-tumour responses. Measuring heterogeneity of pathway inhibition in tissues using protein biomarker...
2.
Goodwin R, Marshall J, Poulogiannis G, Yuneva M, Brindle K, Takats Z, et al.
Cancer Discov
. 2025 Jan;
15(1):34-38.
PMID: 39801233
Understanding tumor heterogeneity is a major challenge that was recognized as one of the first Cancer Grand Challenges, with a call to provide solutions to visualize tumor heterogeneity. The Rosetta...
3.
Chen W, Qiu M, Paizs P, Sadowski M, Ramonaite T, Zborovsky L, et al.
Nat Commun
. 2025 Jan;
16(1):165.
PMID: 39747039
Fast and reliable identification of bacteria directly in clinical samples is a critical factor in clinical microbiological diagnostics. Current approaches require time-consuming bacterial isolation and enrichment procedures, delaying stratified treatment....
4.
Devlin A, Green F, Takats Z
Anal Chem
. 2024 Oct;
96(45):17969-17977.
PMID: 39476845
Previously, spatially resolved analysis of glycosaminoglycans (GAGs), by type and sulfation state, was unobtainable. Here, we describe a mass spectrometry imaging (MSI) approach which enables the detection, identification, localization, and...
5.
Kaufmann M, Vaysse P, Savage A, Kooreman L, Janssen N, Varma S, et al.
Br J Cancer
. 2024 Sep;
131(8):1298-1308.
PMID: 39294437
Background: While REIMS technology has successfully been demonstrated for the histological identification of ex-vivo breast tumor tissues, questions regarding the robustness of the approach and the possibility of tumor molecular...
6.
Brorsen L, McKenzie J, Pinto F, Glud M, Hansen H, Haedersdal M, et al.
Exp Dermatol
. 2024 Jul;
33(7):e15141.
PMID: 39036889
Basal cell carcinoma (BCC), the most common keratinocyte cancer, presents a substantial public health challenge due to its high prevalence. Traditional diagnostic methods, which rely on visual examination and histopathological...
7.
Drouin N, Elfrink H, Boers S, van Hugten S, Wessels E, de Vries J, et al.
Mol Cell Proteomics
. 2024 Jun;
23(7):100805.
PMID: 38897290
Since its first appearance, severe acute respiratory syndrome coronavirus 2 quickly spread around the world and the lack of adequate PCR testing capacities, especially during the early pandemic, led the...
8.
Dannhorn A, Kazanc E, Flint L, Guo F, Carter A, Hall A, et al.
Nat Protoc
. 2024 May;
19(9):2685-2711.
PMID: 38806741
The landscape of tissue-based imaging modalities is constantly and rapidly evolving. While formalin-fixed, paraffin-embedded material is still useful for histological imaging, the fixation process irreversibly changes the molecular composition of...
9.
Brorsen L, McKenzie J, Tullin M, Bendtsen K, Pinto F, Jensen H, et al.
Sci Rep
. 2024 May;
14(1):11091.
PMID: 38750270
Cutaneous squamous cell carcinoma (SCC) is an increasingly prevalent global health concern. Current diagnostic and surgical methods are reliable, but they require considerable resources and do not provide metabolomic insight....
10.
Sekera E, Somogyi A, Takats Z, Stappert F, Thom C, Schmitz O, et al.
J Am Soc Mass Spectrom
. 2024 May;
35(6):1101-1109.
PMID: 38739888
Ion mobility-mass spectrometry (IM-MS) has become increasingly popular with the rapid expansion of available techniques and instrumentation. To enable accuracy, standardization, and repeatability of IM-MS measurements, the community requires reliable...