James S McKenzie
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Explore the profile of James S McKenzie including associated specialties, affiliations and a list of published articles.
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22
Citations
413
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Recent Articles
1.
Chen W, Qiu M, Paizs P, Sadowski M, Ramonaite T, Zborovsky L, et al.
Nat Commun
. 2025 Jan;
16(1):165.
PMID: 39747039
Fast and reliable identification of bacteria directly in clinical samples is a critical factor in clinical microbiological diagnostics. Current approaches require time-consuming bacterial isolation and enrichment procedures, delaying stratified treatment....
2.
Molnar A, Horkovics-Kovats G, Kucsma N, Szego Z, Tauber B, Egri A, et al.
Int J Mol Sci
. 2024 Jul;
25(14).
PMID: 39062995
Breast cancer, a complex disease with a significant prevalence to form metastases, necessitates novel therapeutic strategies to improve treatment outcomes. Here, we present the results of a comparative molecular study...
3.
Brorsen L, McKenzie J, Pinto F, Glud M, Hansen H, Haedersdal M, et al.
Exp Dermatol
. 2024 Jul;
33(7):e15141.
PMID: 39036889
Basal cell carcinoma (BCC), the most common keratinocyte cancer, presents a substantial public health challenge due to its high prevalence. Traditional diagnostic methods, which rely on visual examination and histopathological...
4.
Brorsen L, McKenzie J, Tullin M, Bendtsen K, Pinto F, Jensen H, et al.
Sci Rep
. 2024 May;
14(1):11091.
PMID: 38750270
Cutaneous squamous cell carcinoma (SCC) is an increasingly prevalent global health concern. Current diagnostic and surgical methods are reliable, but they require considerable resources and do not provide metabolomic insight....
5.
Dorado E, Doria M, Nagelkerke A, McKenzie J, Maneta-Stavrakaki S, Whittaker T, et al.
J Extracell Vesicles
. 2024 Mar;
13(3):e12419.
PMID: 38443328
Extracellular vesicles (EVs), including exosomes and microvesicles, mediate intercellular communication in cancer, from development to metastasis. EV-based liquid biopsy is a promising strategy for cancer diagnosis as EVs can be...
6.
Wu V, Tillner J, Jones E, McKenzie J, Gurung D, Mroz A, et al.
Anal Chem
. 2022 Jul;
94(28):10035-10044.
PMID: 35786855
In this study, we examine the suitability of desorption electro-flow focusing ionization (DEFFI) for mass spectrometry imaging (MSI) of biological tissue. We also compare the performance of desorption electrospray ionization...
7.
Isberg O, Giunchiglia V, McKenzie J, Takats Z, Jonasson J, Bodvarsdottir S, et al.
Metabolites
. 2022 May;
12(5).
PMID: 35629959
Optical microscopy has long been the gold standard to analyse tissue samples for the diagnostics of various diseases, such as cancer. The current diagnostic workflow is time-consuming and labour-intensive, and...
8.
Mason S, Manoli E, Alexander J, Poynter L, Ford L, Paizs P, et al.
Ann Surg
. 2021 Aug;
277(3):e569-e577.
PMID: 34387206
Objective: Rapid evaporative ionization mass spectrometry (REIMS) is a metabolomic technique analyzing tissue metabolites, which can be applied intraoperatively in real-time. The objective of this study was to profile the...
9.
Capece D, DAndrea D, Begalli F, Goracci L, Tornatore L, Alexander J, et al.
J Clin Invest
. 2021 Apr;
131(11).
PMID: 33878036
The ability to adapt to low-nutrient microenvironments is essential for tumor cell survival and progression in solid cancers, such as colorectal carcinoma (CRC). Signaling by the NF-κB transcription factor pathway...
10.
Abbassi-Ghadi N, Antonowicz S, McKenzie J, Kumar S, Huang J, Jones E, et al.
Cancer Res
. 2020 Apr;
80(13):2764-2774.
PMID: 32345674
The incidence of esophageal adenocarcinoma is rising, survival remains poor, and new tools to improve early diagnosis and precise treatment are needed. Cancer phospholipidomes quantified with mass spectrometry imaging (MSI)...