Zoe Urry
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Explore the profile of Zoe Urry including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Chambers E, Suwannasaen D, Mann E, Urry Z, Richards D, Lertmemongkolchai G, et al.
Immunology
. 2014 Mar;
143(1):52-60.
PMID: 24673126
A high prevalence of vitamin D insufficiency and deficiency exists worldwide, which is associated with an increased incidence and severity of a range of immune-mediated diseases. This has resulted in...
2.
Gupta A, Dimeloe S, Richards D, Chambers E, Black C, Urry Z, et al.
Thorax
. 2013 Dec;
69(6):508-15.
PMID: 24347461
Background: Understanding of immune mechanisms underpinning asthma has emerged from studies in adults. It is increasingly recognised, both immunologically and in the development of novel therapies, that adult responses cannot...
3.
Cullup T, Kho A, Dionisi-Vici C, Brandmeier B, Smith F, Urry Z, et al.
Nat Genet
. 2012 Dec;
45(1):83-7.
PMID: 23222957
Vici syndrome is a recessively inherited multisystem disorder characterized by callosal agenesis, cataracts, cardiomyopathy, combined immunodeficiency and hypopigmentation. To investigate the molecular basis of Vici syndrome, we carried out exome...
4.
Urry Z, Chambers E, Xystrakis E, Dimeloe S, Richards D, Gabrysova L, et al.
Eur J Immunol
. 2012 Aug;
42(10):2697-708.
PMID: 22903229
1α,25-Dihydroxyvitamin D3 (1α25VitD3) has potent immunomodulatory properties. We have previously demonstrated that 1α25VitD3 promotes human and murine IL-10-secreting CD4(+) T cells. Because of the clinical relevance of this observation, we...
5.
Urry Z, Xystrakis E, Richards D, McDonald J, Sattar Z, Cousins D, et al.
J Clin Invest
. 2009 Jan;
119(2):387-98.
PMID: 19139565
Signaling through the TLR family of molecular pattern recognition receptors has been implicated in the induction of innate and adaptive immune responses. A role for TLR signaling in the maintenance...
6.
Xystrakis E, Urry Z, Hawrylowicz C
Curr Opin Allergy Clin Immunol
. 2007 Nov;
7(6):535-41.
PMID: 17989531
Purpose Of Review: Regulatory T cells have been identified as key players in the maintenance of peripheral tolerance, which prevents inappropriate immune responses to both self-antigens and innocuous allergens. This...
7.
Faith A, Peek E, McDonald J, Urry Z, Richards D, Tan C, et al.
Am J Respir Cell Mol Biol
. 2006 Oct;
36(3):360-7.
PMID: 17023687
Dendritic cells (DC) resident in draining lymph nodes (LN) of patients with lung cancer are proposed to have a critical role in stimulating anti-tumor immunity. CpG oligodeoxynucleotides are undergoing clinical...
8.
Urry Z, Xystrakis E, Hawrylowicz C
Curr Allergy Asthma Rep
. 2006 Aug;
6(5):363-71.
PMID: 16899197
Allergic diseases, including asthma, are chronic inflammatory disorders originating from an aberrant immune response to innocuous antigens in our environment (allergens). In susceptible individuals, sensitization to allergen leads to the...
9.
Xystrakis E, Kusumakar S, Boswell S, Peek E, Urry Z, Richards D, et al.
J Clin Invest
. 2005 Dec;
116(1):146-55.
PMID: 16341266
We previously reported that human CD4+ Tregs secrete high levels of IL-10 when stimulated in the presence of dexamethasone and calcitriol (vitamin D3). We now show that following stimulation by...
10.
Lean J, Kirstein B, Urry Z, Chambers T, Fuller K
Biochem Biophys Res Commun
. 2004 Sep;
321(4):845-50.
PMID: 15358104
We found that the antioxidant protein thioredoxin-1 (Trx) is more highly expressed in osteoclasts than in macrophages. Moreover, transfection of RAW 264.7 (RAW) cells with a Trx-expression construct resulted in...