David F Richards
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Explore the profile of David F Richards including associated specialties, affiliations and a list of published articles.
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28
Citations
1170
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Recent Articles
1.
Dimeloe S, Rice L, Chen H, Cheadle C, Raynes J, Pfeffer P, et al.
J Steroid Biochem Mol Biol
. 2019 Jan;
189:1-9.
PMID: 30690074
Studies to identify novel immune-regulatory functions of active vitamin D (1,25(OH)D3) in human CD4 T cells revealed that 1,25(OH)D3 potently induced expression of the gene SERPINA1, encoding the anti-protease α-1-antitrypsin....
2.
Cranford J, OHara T, Villongco C, Hafez O, Blake R, Loscalzo J, et al.
Cardiovasc Eng Technol
. 2018 Mar;
9(3):447-467.
PMID: 29549620
Patient-specific models of the ventricular myocardium, combined with the computational power to run rapid simulations, are approaching the level where they could be used for personalized cardiovascular medicine. A major...
3.
Mann E, Chambers E, Chen Y, Richards D, Hawrylowicz C
Immunology
. 2015 Aug;
146(3):423-31.
PMID: 26251265
Vitamin D deficiency is associated with increased incidence and severity of various immune-mediated diseases. Active vitamin D (1α,25-dihydroxyvitamin D3; 1,25(OH)2 D3) up-regulates CD4(+) T-cell expression of the purine ectonucleotidase CD39,...
4.
Chambers E, Nanzer A, Pfeffer P, Richards D, Timms P, Martineau A, et al.
J Allergy Clin Immunol
. 2015 Mar;
136(3):628-637.e4.
PMID: 25772594
Background: A small population of patients with severe asthma does not respond to glucocorticoids (steroid resistant [SR]). They have high morbidity, highlighting an urgent need for strategies to enhance glucocorticoid...
5.
Gurev V, Pathmanathan P, Fattebert J, Wen H, Magerlein J, Gray R, et al.
Biomech Model Mechanobiol
. 2015 Jan;
14(4):829-49.
PMID: 25567753
Modeling of the heart ventricles is one of the most challenging tasks in soft tissue mechanics because cardiac tissue is a strongly anisotropic incompressible material with an active component of...
6.
Urry Z, Richards D, Black C, Morales M, Carnes J, Hawrylowicz C, et al.
BMC Immunol
. 2014 Jun;
15:21.
PMID: 24884430
Background: Allergen immunotherapy (SIT) is the only treatment for allergic disease capable of modifying disease long term. To reduce the risk of anaphylaxis from SIT, allergen-extracts have been modified by...
7.
Nanzer A, Chambers E, Ryanna K, Freeman A, Colligan G, Richards D, et al.
J Allergy Clin Immunol
. 2014 May;
133(6):1755-7.e4.
PMID: 24786237
No abstract available.
8.
Chambers E, Suwannasaen D, Mann E, Urry Z, Richards D, Lertmemongkolchai G, et al.
Immunology
. 2014 Mar;
143(1):52-60.
PMID: 24673126
A high prevalence of vitamin D insufficiency and deficiency exists worldwide, which is associated with an increased incidence and severity of a range of immune-mediated diseases. This has resulted in...
9.
Gupta A, Dimeloe S, Richards D, Chambers E, Black C, Urry Z, et al.
Thorax
. 2013 Dec;
69(6):508-15.
PMID: 24347461
Background: Understanding of immune mechanisms underpinning asthma has emerged from studies in adults. It is increasingly recognised, both immunologically and in the development of novel therapies, that adult responses cannot...
10.
Grabowski P, Surh M, Richards D, Graziani F, Murillo M
Phys Rev Lett
. 2013 Dec;
111(21):215002.
PMID: 24313494
Molecular dynamics can provide very accurate tests of classical kinetic theory; for example, unambiguous comparisons can be made for classical particles interacting via a repulsive 1/r potential. The plasma stopping...