Zhung-Fu Lee
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Explore the profile of Zhung-Fu Lee including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
88
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Recent Articles
1.
Bosquez Huerta N, Lee Z, Christine Song E, Woo J, Cheng Y, Sardar D, et al.
Cell Rep
. 2024 Dec;
44(1):115121.
PMID: 39731735
Astrocytes exhibit diverse cellular and molecular properties across the central nervous system (CNS). Recent studies identified region-specific transcription factors (TF) that oversee these diverse properties; how sex differences intersect with...
2.
Tumor Expression of CD83 Reduces Glioma Progression and Is Associated with Reduced Immunosuppression
McDonald M, Curry R, OReilly I, Lozzi B, Cervantes A, Lee Z, et al.
Cancer Res Commun
. 2024 Nov;
4(12):3209-3223.
PMID: 39601621
Immunosuppression in malignant glioma remains a barrier to therapeutic development. CD83 overexpression in human and mouse glioma increases survival. CD83+ tumor cells promote signatures related to cytotoxic T cells, enhanced...
3.
Huang-Hobbs E, Cheng Y, Ko Y, Luna-Figueroa E, Lozzi B, Taylor K, et al.
Nature
. 2023 Jun;
619(7971):844-850.
PMID: 37380778
The tumour microenvironment plays an essential role in malignancy, and neurons have emerged as a key component of the tumour microenvironment that promotes tumourigenesis across a host of cancers. Recent...
4.
Sardar D, Cheng Y, Woo J, Choi D, Lee Z, Kwon W, et al.
Science
. 2023 Jun;
380(6650):eade0027.
PMID: 37319217
Neuronal activity drives alterations in gene expression within neurons, yet how it directs transcriptional and epigenomic changes in neighboring astrocytes in functioning circuits is unknown. We found that neuronal activity...
5.
Cheng Y, Luna-Figueroa E, Woo J, Chen H, Lee Z, Harmanci A, et al.
Nature
. 2023 Apr;
617(7960):369-376.
PMID: 37100909
Communication between neurons and glia has an important role in establishing and maintaining higher-order brain function. Astrocytes are endowed with complex morphologies, placing their peripheral processes in close proximity to...
6.
Huang-Hobbs E, Cheng Y, Ko Y, Luna-Figueroa E, Lozzi B, Taylor K, et al.
bioRxiv
. 2023 Mar;
PMID: 36993539
The tumor microenvironment (TME) plays an essential role in malignancy and neurons have emerged as a key component of the TME that promotes tumorigenesis across a host of cancers. Recent...
7.
Cheng Y, Luna-Figueroa E, Woo J, Chen H, Lee Z, Harmanci A, et al.
bioRxiv
. 2023 Mar;
PMID: 36993256
Communication between neurons and glia plays an important role in establishing and maintaining higher order brain function. Astrocytes are endowed with complex morphologies which places their peripheral processes in close...
8.
Sardar D, Cheng Y, Woo J, Choi D, Lee Z, Kwon W, et al.
bioRxiv
. 2023 Mar;
PMID: 36909526
Neuronal activity drives global alterations in gene expression within neurons, yet how it directs transcriptional and epigenomic changes in neighboring astrocytes in functioning circuits is unknown. Here we show that...
9.
CGRP-dependent sensitization of PKC-δ positive neurons in central amygdala mediates chronic migraine
Chou T, Lee Z, Wang S, Lien C, Chen S
J Headache Pain
. 2022 Dec;
23(1):157.
PMID: 36510143
Background: To investigate specific brain regions and neural circuits that are responsible for migraine chronification. Methods: We established a mouse model of chronic migraine with intermittent injections of clinically-relevant dose...
10.
Lee Z, Huang T, Chen S, Cheng I
Pain
. 2021 Jan;
162(6):1669-1680.
PMID: 33433143
Alzheimer disease (AD) is the most common form of dementia, accounting for approximately 60% of cases. In addition to memory loss, changes in pain sensitivity are found in a substantial...