Akdes Serin Harmanci
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Explore the profile of Akdes Serin Harmanci including associated specialties, affiliations and a list of published articles.
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32
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834
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Recent Articles
1.
Curry R, McDonald M, He P, Lozzi B, Ko Y, OReilly I, et al.
bioRxiv
. 2025 Mar;
PMID: 40060572
Non-canonical roles for growth factors in the nucleus have been previously described, but their mechanism of action and biological roles remain enigmatic. Platelet-derived growth factor B (PDGFB) can drive formation...
2.
McGinnis J, Ortiz-Guzman J, Mallannagari S, Guevara M, Belfort B, Bao S, et al.
bioRxiv
. 2025 Jan;
PMID: 39763930
It is becoming more broadly accepted that human-based models are needed to better understand the complexities of the human nervous system and its diseases. The recently developed human brain organotypic...
3.
Bosquez Huerta N, Lee Z, Christine Song E, Woo J, Cheng Y, Sardar D, et al.
Cell Rep
. 2024 Dec;
44(1):115121.
PMID: 39731735
Astrocytes exhibit diverse cellular and molecular properties across the central nervous system (CNS). Recent studies identified region-specific transcription factors (TF) that oversee these diverse properties; how sex differences intersect with...
4.
McGinnis J, Ortiz-Guzman J, Guevara M, Mallannagari S, Belfort B, Bao S, et al.
bioRxiv
. 2024 Nov;
PMID: 39605617
The development of cell-type-specific gene therapy vectors for treating neurological diseases holds great promise, but has relied on animal models with limited translational utility. We have adapted an organotypic model...
5.
Tumor Expression of CD83 Reduces Glioma Progression and Is Associated with Reduced Immunosuppression
McDonald M, Curry R, OReilly I, Lozzi B, Cervantes A, Lee Z, et al.
Cancer Res Commun
. 2024 Nov;
4(12):3209-3223.
PMID: 39601621
Immunosuppression in malignant glioma remains a barrier to therapeutic development. CD83 overexpression in human and mouse glioma increases survival. CD83+ tumor cells promote signatures related to cytotoxic T cells, enhanced...
6.
Curry R, Ma Q, McDonald M, Ko Y, Srivastava S, Chin P, et al.
Cancer Cell
. 2024 Sep;
42(10):1713-1728.e6.
PMID: 39241781
Prior studies have described the complex interplay that exists between glioma cells and neurons; however, the electrophysiological properties endogenous to glioma cells remain obscure. To address this, we employed Patch-sequencing...
7.
Shetty A, Wang S, Khan A, English C, Hosseingholi Nouri S, Magill S, et al.
J Neurooncol
. 2024 Jun;
168(3):525.
PMID: 38834749
No abstract available.
8.
Shetty A, Wang S, Khan A, English C, Hosseingholi Nouri S, Magill S, et al.
J Neurooncol
. 2024 May;
168(3):515-524.
PMID: 38811523
Purpose: Accurate classification of cancer subgroups is essential for precision medicine, tailoring treatments to individual patients based on their cancer subtypes. In recent years, advances in high-throughput sequencing technologies have...
9.
Curry R, Ma Q, McDonald M, Ko Y, Srivastava S, Chin P, et al.
bioRxiv
. 2024 Mar;
PMID: 38496434
Prior studies have described the complex interplay that exists between glioma cells and neurons, however, the electrophysiological properties endogenous to tumor cells remain obscure. To address this, we employed Patch-sequencing...
10.
Youngblood M, Erson-Omay Z, Li C, Najem H, Coskun S, Tyrtova E, et al.
Nat Commun
. 2023 Oct;
14(1):6279.
PMID: 37805627
Hedgehog signaling mediates embryologic development of the central nervous system and other tissues and is frequently hijacked by neoplasia to facilitate uncontrolled cellular proliferation. Meningiomas, the most common primary brain...