Brittney Lozzi
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Explore the profile of Brittney Lozzi including associated specialties, affiliations and a list of published articles.
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23
Citations
388
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Recent Articles
1.
Curry R, McDonald M, He P, Lozzi B, Ko Y, OReilly I, et al.
bioRxiv
. 2025 Mar;
PMID: 40060572
Non-canonical roles for growth factors in the nucleus have been previously described, but their mechanism of action and biological roles remain enigmatic. Platelet-derived growth factor B (PDGFB) can drive formation...
2.
Tumor Expression of CD83 Reduces Glioma Progression and Is Associated with Reduced Immunosuppression
McDonald M, Curry R, OReilly I, Lozzi B, Cervantes A, Lee Z, et al.
Cancer Res Commun
. 2024 Nov;
4(12):3209-3223.
PMID: 39601621
Immunosuppression in malignant glioma remains a barrier to therapeutic development. CD83 overexpression in human and mouse glioma increases survival. CD83+ tumor cells promote signatures related to cytotoxic T cells, enhanced...
3.
Curry R, Ma Q, McDonald M, Ko Y, Srivastava S, Chin P, et al.
Cancer Cell
. 2024 Sep;
42(10):1713-1728.e6.
PMID: 39241781
Prior studies have described the complex interplay that exists between glioma cells and neurons; however, the electrophysiological properties endogenous to glioma cells remain obscure. To address this, we employed Patch-sequencing...
4.
Chen H, He P, McDonald M, Williamson M, Varadharajan S, Lozzi B, et al.
Nature
. 2024 Jul;
632(8026):903-910.
PMID: 39085609
Bidirectional communication between tumours and neurons has emerged as a key facet of the tumour microenvironment that drives malignancy. Another hallmark feature of cancer is epigenomic dysregulation, in which alterations...
5.
Spencer L, Costine B, Irwin T, Dixit A, Spern C, Diaz A, et al.
Microorganisms
. 2024 Mar;
12(3).
PMID: 38543566
Ionic silver (Ag) is being investigated as a residual biocide for use in NASA spacecraft potable water systems on future crewed missions. This water will be used to irrigate future...
6.
Curry R, Ma Q, McDonald M, Ko Y, Srivastava S, Chin P, et al.
bioRxiv
. 2024 Mar;
PMID: 38496434
Prior studies have described the complex interplay that exists between glioma cells and neurons, however, the electrophysiological properties endogenous to tumor cells remain obscure. To address this, we employed Patch-sequencing...
7.
Huang-Hobbs E, Cheng Y, Ko Y, Luna-Figueroa E, Lozzi B, Taylor K, et al.
Nature
. 2023 Jun;
619(7971):844-850.
PMID: 37380778
The tumour microenvironment plays an essential role in malignancy, and neurons have emerged as a key component of the tumour microenvironment that promotes tumourigenesis across a host of cancers. Recent...
8.
Sardar D, Cheng Y, Woo J, Choi D, Lee Z, Kwon W, et al.
Science
. 2023 Jun;
380(6650):eade0027.
PMID: 37319217
Neuronal activity drives alterations in gene expression within neurons, yet how it directs transcriptional and epigenomic changes in neighboring astrocytes in functioning circuits is unknown. We found that neuronal activity...
9.
Choi D, Armstrong G, Lozzi B, Vijayaraghavan P, Plon S, Wong T, et al.
Sci Adv
. 2023 Apr;
9(17):eade2675.
PMID: 37115922
Glioma is a rare brain tumor with a poor prognosis. Familial glioma is a subset of glioma with a strong genetic predisposition that accounts for approximately 5% of glioma cases....
10.
Huang-Hobbs E, Cheng Y, Ko Y, Luna-Figueroa E, Lozzi B, Taylor K, et al.
bioRxiv
. 2023 Mar;
PMID: 36993539
The tumor microenvironment (TME) plays an essential role in malignancy and neurons have emerged as a key component of the TME that promotes tumorigenesis across a host of cancers. Recent...