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Zhigang Hong

Explore the profile of Zhigang Hong including associated specialties, affiliations and a list of published articles. Areas
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Articles 55
Citations 3032
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Recent Articles
1.
Ly M, Diaz-Garcia S, Roscoe N, Ushach I, Hong Z, Franca M, et al.
Toxicol Pathol . 2025 Jan; 1926233241311539. PMID: 39829074
Small interfering RNAs (siRNAs) have been successfully used as therapeutics to silence disease-causing genes when conjugated to ligands or formulated in lipid nanoparticles to target relevant cell types for efficacy...
2.
Liao L, Tang J, Hong Z, Jiang W, Li Y, Kong L, et al.
BMC Cancer . 2024 Feb; 24(1):164. PMID: 38302968
Background: For high-risk stageIImismatch repair deficient (dMMR) colon cancers, the benefit of adjuvant chemotherapy remains debatable. The principal aim of this study was to evaluate the prognostic value of high-risk...
3.
Li Y, Li B, Jiang R, Liao L, Zheng C, Yuan J, et al.
Cancer Med . 2023 Oct; 12(21):20626-20638. PMID: 37881109
Background: Colorectal cancer (CRC) is one of the most common malignancies, and early detection plays a crucial role in enhancing curative outcomes. While colonoscopy is considered the gold standard for...
4.
Xiong S, Hong Z, Huang L, Tsukasaki Y, Nepal S, Di A, et al.
J Clin Invest . 2023 Mar; 133(5). PMID: 36856118
No abstract available.
5.
Zhang L, Deng Y, Liu S, Zhang W, Hong Z, Lu Z, et al.
BMC Cancer . 2023 Jan; 23(1):3. PMID: 36593480
Background: Lymphovascular invasion (LVI) and perineural invasion (PNI) can indicate poor survival outcomes in colorectal cancer, but few studies have focused on stage III colon cancer. The current study aimed...
6.
Li Y, Liao L, Kong L, Jiang W, Tang J, Han K, et al.
Clin Transl Oncol . 2022 Sep; 25(1):218-225. PMID: 36076121
Background: For clinically low-risk stage III colorectal cancer, the decision on cycles of adjuvant chemotherapy after surgery is disputed. The present study investigates the use of additional biomarkers of ploidy...
7.
Lin J, Sun H, Zhang W, Hong Z, Lu Z, Pan Z, et al.
Cancer Med . 2022 Apr; 11(22):4225-4235. PMID: 35466587
Background: The number of colorectal cancer liver metastases (CRLMs) is usually considered a contradictory indicator to surgical resection. However, some patients with initially unresectable CRLMs can receive radical local treatment...
8.
Bachmaier K, Stuart A, Singh A, Mukhopadhyay A, Chakraborty S, Hong Z, et al.
ACS Nano . 2022 Mar; 16(3):4084-4101. PMID: 35230826
The complex involvement of neutrophils in inflammatory diseases makes them intriguing but challenging targets for therapeutic intervention. Here, we tested the hypothesis that varying endocytosis capacities would delineate functionally distinct...
9.
Li X, Zhang W, Ding P, Guo R, Hong Z, Liu P, et al.
Int J Colorectal Dis . 2021 Jan; 36(6):1201-1208. PMID: 33511478
Purpose: As a kind of secondary tumor of the ovary, ovarian metastasis from colorectal cancer (OMCRC) happens rarely. Prognostic factors of OMCRC are still undetermined. This study was conducted to...
10.
Zhou B, Magana L, Hong Z, Huang L, Chakraborty S, Tsukasaki Y, et al.
Nat Immunol . 2020 Aug; 21(11):1430-1443. PMID: 32839607
Macrophages demonstrate remarkable plasticity that is essential for host defense and tissue repair. The tissue niche imprints macrophage identity, phenotype and function. The role of vascular endothelial signals in tailoring...