Glenn Marsboom
Overview
Explore the profile of Glenn Marsboom including associated specialties, affiliations and a list of published articles.
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37
Citations
2519
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Recent Articles
1.
Ly M, Diaz-Garcia S, Roscoe N, Ushach I, Hong Z, Franca M, et al.
Toxicol Pathol
. 2025 Jan;
1926233241311539.
PMID: 39829074
Small interfering RNAs (siRNAs) have been successfully used as therapeutics to silence disease-causing genes when conjugated to ligands or formulated in lipid nanoparticles to target relevant cell types for efficacy...
2.
Krantz S, Kim Y, Srivastava S, Leasure J, Toth P, Marsboom G, et al.
J Biol Chem
. 2021 Nov;
297(6):101410.
PMID: 34785214
Pluripotent stem cells are known to shift their mitochondrial metabolism upon differentiation, but the mechanisms underlying such metabolic rewiring are not fully understood. We hypothesized that during differentiation of human...
3.
Liu B, Zhu L, Yuan P, Marsboom G, Hong Z, Liu J, et al.
Am J Physiol Cell Physiol
. 2020 Mar;
318(5):C913-C930.
PMID: 32159364
Whole exome sequencing (WES) was used in the research of familial pulmonary arterial hypertension (FPAH). and were found as two novel candidate genes of FPAH. However, few pathogenic genes were...
4.
Liu M, Zhang L, Marsboom G, Jambusaria A, Xiong S, Toth P, et al.
Nat Commun
. 2019 May;
10(1):2126.
PMID: 31073164
Repair of the endothelial cell barrier after inflammatory injury is essential for tissue fluid homeostasis and normalizing leukocyte transmigration. However, the mechanisms of endothelial regeneration remain poorly understood. Here we...
5.
Marsboom G, Rehman J
Physiology (Bethesda)
. 2018 Aug;
33(5):328-337.
PMID: 30109825
Hypoxia signaling in the vasculature controls vascular permeability, inflammation, vascular growth, and repair of vascular injury. In this review, we summarize recent insights in this burgeoning field and highlight the...
6.
Marsboom G, Chen Z, Yuan Y, Zhang Y, Tiruppathi C, Loyd J, et al.
Mol Biol Cell
. 2017 May;
28(9):1177-1185.
PMID: 28468941
A heterozygous caveolin-1 c.474delA mutation has been identified in a family with heritable pulmonary arterial hypertension (PAH). This frameshift mutation leads to a caveolin-1 protein that contains all known functional...
7.
Zhang L, Jambusaria A, Hong Z, Marsboom G, Toth P, Herbert B, et al.
Circulation
. 2017 Apr;
135(25):2505-2523.
PMID: 28381471
Background: The mechanisms underlying the dedifferentiation and lineage conversion of adult human fibroblasts into functional endothelial cells have not yet been fully defined. Furthermore, it is not known whether fibroblast...
8.
Marsboom G, Chen Z, Yuan Y, Zhang Y, Tiruppathi C, Loyd J, et al.
Mol Biol Cell
. 2017 Mar;
PMID: 28298490
A heterozygous Caveolin-1 c.474delA mutation has been identified in a family with heritable pulmonary arterial hypertension (PAH). This frameshift mutation leads to caveolin-1 protein that contains all known functional domains...
9.
Marsboom G, Rehman J
Oncotarget
. 2016 Nov;
7(49):80107-80108.
PMID: 27876699
No abstract available.
10.
Marsboom G, Zhang G, Pohl-Avila N, Zhang Y, Yuan Y, Kang H, et al.
Cell Rep
. 2016 Jun;
16(2):323-332.
PMID: 27346346
The molecular mechanisms underlying the regulation of pluripotency by cellular metabolism in human embryonic stem cells (hESCs) are not fully understood. We found that high levels of glutamine metabolism are...