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Zeinab Abdullah

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Articles 48
Citations 1683
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Recent Articles
1.
Greiner-Tollersrud O, Krausz M, Boehler V, Polyzou A, Seidl M, Spahiu A, et al.
Cell Rep . 2024 Oct; 43(11):114899. PMID: 39441717
Although adenosine deaminase 2 (ADA2) is considered an extracellular ADA, evidence questions the physiological relevance of this activity. Our study reveals that ADA2 localizes within the lysosomes, where it is...
2.
Jacob A, Lindemann A, Wagenpfeil J, Geiger S, Layer Y, Salam B, et al.
Sci Rep . 2024 Aug; 14(1):18033. PMID: 39098935
Light sheet fluorescence microscopy (LSFM) is a transformative imaging method that enables the visualization of non-dissected specimen in real-time 3D. Optical clearing of tissues is essential for LSFM, typically employing...
3.
Schloesser L, Klose S, Mauschitz M, Abdullah Z, Finger R
Surv Ophthalmol . 2024 Aug; 69(6):851-869. PMID: 39097172
We provide an overview of the expanding literature on the role of cytokines and immune mediators in pathophysiology of age-related macular degeneration (AMD). Although many immunological mediators have been linked...
4.
Graelmann F, Gondorf F, Majlesain Y, Niemann B, Klepac K, Gosejacob D, et al.
Mol Metab . 2024 May; 85:101963. PMID: 38821174
Objective: The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor regulating xenobiotic responses as well as physiological metabolism. Dietary AhR ligands activate the AhR signaling axis, whereas AhR activation...
5.
Bohner A, Effland A, Jacob A, Bohner K, Abdullah Z, Brahler S, et al.
Kidney Int . 2024 Mar; 105(6):1254-1262. PMID: 38458475
Three-dimensional (3D) imaging has advanced basic research and clinical medicine. However, limited resolution and imperfections of real-world 3D image material often preclude algorithmic image analysis. Here, we present a methodologic...
6.
Chang Y, Bach L, Hasiuk M, Wen L, Elmzzahi T, Tsui C, et al.
Sci Immunol . 2024 Mar; 9(93):eadd4818. PMID: 38427718
T follicular helper (T) cells are essential for effective antibody responses, but deciphering the intrinsic wiring of mouse T cells has long been hampered by the lack of a reliable...
7.
Nickenig M, Mangan M, Lee H, Symeonidis K, Henne A, Kaiser R, et al.
J Immunol . 2023 Dec; 212(1):7-11. PMID: 38038390
The 2'3'-cyclic GMP-AMP (cGAMP) synthase (cGAS)-stimulator of IFN genes (STING) pathway can sense infection and cellular stress by detecting cytosolic DNA. Upon ligand binding, cGAS produces the cyclic dinucleotide messenger...
8.
Sun Z, Cernilogar F, Horvatic H, Yeroslaviz A, Abdullah Z, Schotta G, et al.
Cell Rep . 2023 Oct; 42(11):113322. PMID: 37883227
Fibrosis, characterized by sustained activation of myofibroblasts and excessive extracellular matrix (ECM) deposition, is known to be associated with chronic inflammation. Receptor-interacting protein kinase 3 (RIPK3), the central kinase of...
9.
Yin J, Mei Q, Prinz M, Abdullah Z, Panzer U, Li J, et al.
Kidney Int . 2023 Jun; 104(3):605-610. PMID: 37290602
No abstract available.
10.
Kotsiliti E, Leone V, Schuehle S, Govaere O, Li H, Wolf M, et al.
J Hepatol . 2023 May; 79(2):296-313. PMID: 37224925
Background & Aims: The progression of non-alcoholic steatohepatitis (NASH) to fibrosis and hepatocellular carcinoma (HCC) is aggravated by auto-aggressive T cells. The gut-liver axis contributes to NASH, but the mechanisms...