Zeenia Kaul
Overview
Explore the profile of Zeenia Kaul including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
698
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0
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Recent Articles
1.
Kaul Z, Cheung C, Bhargava P, Sari A, Yu Y, Huifu H, et al.
Sci Rep
. 2021 Aug;
11(1):17052.
PMID: 34426596
Activation of a telomere length maintenance mechanism (TMM), including telomerase and alternative lengthening of telomeres (ALT), is essential for replicative immortality of tumor cells, although its regulatory mechanisms are incompletely...
2.
Li L, Gao R, Yu Y, Kaul Z, Wang J, Kalra R, et al.
Sci Rep
. 2018 Jan;
8(1):375.
PMID: 29321561
microRNAs (miRs) have recently emerged as small non-coding regulators of gene expression. We performed a loss-of-function screening by recruiting retrovirus mediated arbitrary manipulation of genome coupled with escape of cells...
3.
Yu Y, Katiyar S, Sundar D, Kaul Z, Miyako E, Zhang Z, et al.
Cell Death Dis
. 2017 Apr;
8(4):e2755.
PMID: 28425984
Maintenance of telomere length is the most consistent attribute of cancer cells. Tightly connected to their capacity to overcome replicative mortality, it is achieved either by activation of telomerase or...
4.
Martinez A, Kaul Z, Parvin J, Groden J
Genes Chromosomes Cancer
. 2017 Apr;
56(8):617-631.
PMID: 28398700
Cancer cells require telomere maintenance to enable uncontrolled growth. Most often telomerase is activated, although a subset of human cancers are telomerase-negative and depend on recombination-based mechanisms known as ALT...
5.
Yu Y, Gao R, Kaul Z, Li L, Kato Y, Zhang Z, et al.
Sci Rep
. 2016 Jul;
6:30185.
PMID: 27457128
Significance of microRNAs (miRs), small non-coding molecules, has been implicated in a variety of biological processes. Here, we recruited retroviral insertional mutagenesis to obtain induction of an arbitrary noncoding RNAs,...
6.
Na Y, Kaul S, Ryu J, Lee J, Ahn H, Kaul Z, et al.
Cancer Res
. 2016 Mar;
76(9):2754-2765.
PMID: 26960973
Mortalin/mthsp70 (HSPA9) is a stress chaperone enriched in many cancers that has been implicated in carcinogenesis by promoting cell proliferation and survival. In the present study, we examined the clinical...
7.
Acharya S, Kaul Z, Gocha A, Martinez A, Harris J, Parvin J, et al.
PLoS One
. 2014 Aug;
9(8):e103819.
PMID: 25084169
Fifteen percent of tumors utilize recombination-based alternative lengthening of telomeres (ALT) to maintain telomeres. The mechanisms underlying ALT are unclear but involve several proteins involved in homologous recombination including the...
8.
Ryu J, Kaul Z, Yoon A, Liu Y, Yaguchi T, Na Y, et al.
J Biol Chem
. 2014 Jul;
289(36):24832-44.
PMID: 25012652
The Hsp70 family protein mortalin is an essential chaperone that is frequently enriched in cancer cells and exists in various subcellular sites, including the mitochondrion, plasma membrane, endoplasmic reticulum, and...
9.
Gao R, Singh R, Kaul Z, Kaul S, Wadhwa R
J Gerontol A Biol Sci Med Sci
. 2014 Apr;
70(6):701-13.
PMID: 24747666
The heat shock 70 family protein, mortalin, has pancytoplasmic distribution pattern in normal and perinuclear in cancer human cells. Cancer cells when induced to senesce by either chemicals or stress...
10.
Singh R, Kalra R, Hasan K, Kaul Z, Cheung C, Huschtscha L, et al.
Exp Cell Res
. 2014 Feb;
322(2):324-34.
PMID: 24485912
CARF is an ARF-binding protein that has been shown to regulate the p53-p21-HDM2 pathway. CARF overexpression was shown to cause growth arrest of human cancer cells and premature senescence of...