Zachary J Carter
Overview
Explore the profile of Zachary J Carter including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
11
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Recent Articles
1.
Prucha G, Henry S, Hollander K, Carter Z, Spasov K, Jorgensen W, et al.
Eur J Med Chem
. 2023 Oct;
262:115894.
PMID: 37883896
Reverse transcriptase (RT) is one of three key proteins responsible for the replication cycle of HIV-1 in the host. Several classes of inhibitors have been developed to target the enzyme,...
2.
Carter Z, Hollander K, Spasov K, Anderson K, Jorgensen W
Bioorg Med Chem Lett
. 2023 Mar;
84:129216.
PMID: 36871704
We report non-nucleoside inhibitors of HIV-1 reverse transcriptase (NNRTIs) using a biphenylmethyloxazole pharmacophore. A crystal structure of benzyloxazole 1 was obtained and suggested the potential viability of biphenyl analogues. In...
3.
Ippolito J, Niu H, Bertoletti N, Carter Z, Jin S, Spasov K, et al.
ACS Med Chem Lett
. 2021 Feb;
12(2):249-255.
PMID: 33603971
Covalent inhibitors of wild-type HIV-1 reverse transcriptase (CRTIs) are reported. Three compounds derived from catechol diether non-nucleoside inhibitors (NNRTIs) with addition of a fluorosulfate warhead are demonstrated to covalently modify...