Yusuke Higashi
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Explore the profile of Yusuke Higashi including associated specialties, affiliations and a list of published articles.
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60
Citations
1523
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Recent Articles
1.
Higashi Y, Dashek R, Delafontaine P, Rector R, Chandrasekar B
Cells
. 2024 Oct;
13(20.
PMID: 39451191
Curcumin, a polyphenolic compound derived from the widely used spice has shown anti-atherosclerotic effects in animal models and cultured vascular cells. Inflammation is a major contributor to atherosclerosis development and...
2.
Sharma N, Khalyfa A, Cai D, Morales-Quinones M, Soares R, Higashi Y, et al.
J Appl Physiol (1985)
. 2024 Jun;
137(3):527-539.
PMID: 38867666
Obstructive sleep apnea (OSA), characterized by episodes of intermittent hypoxia (IH), is highly prevalent in patients with abdominal aortic aneurysm (AAA). However, whether IH serves as an independent risk factor...
3.
Higashi Y, Shima K, Suzuki M, Fujishiro M, Kawai T, Morimoto T
J Org Chem
. 2024 Mar;
89(6):3962-3969.
PMID: 38443796
We have found a novel method for introducing heptafluoro-2-propyl CF(CF) groups into carbon-carbon unsaturated bonds via a nucleophilic reaction using 2-heptafluoropropane as the source of CF(CF) groups. The reaction involves...
4.
Chandrasekar B, Mummidi S, Demarco V, Higashi Y
Mediators Inflamm
. 2023 Oct;
2023:6112301.
PMID: 37830075
Persistent oxidative stress and inflammation contribute causally to smooth muscle cell (SMC) proliferation and migration, the characteristic features of vascular proliferative diseases. Oxidatively modified low-density lipoproteins (OxLDL) elevate oxidative stress...
5.
Alluri S, Higashi Y, Berendzen A, Grisanti L, Watkinson L, Singh K, et al.
EJNMMI Res
. 2023 Jul;
13(1):67.
PMID: 37438543
Background: CXCR3 is a chemokine receptor and is expressed in innate and adaptive immune cells. It promotes the recruitment of T-lymphocytes and other immune cells to the inflammatory site in...
6.
Alluri S, Higashi Y, Berendzen A, Grisanti L, Watkinson L, Singh K, et al.
Res Sq
. 2023 Mar;
PMID: 36865232
CXCR3 is a chemokine receptor and is expressed on innate and adaptive immune cells. It promotes the recruitment of T-lymphocytes and other immune cells to the inflammatory site in response...
7.
Sukhanov S, Higashi Y, Yoshida T, Danchuk S, Alfortish M, Goodchild T, et al.
JCI Insight
. 2023 Jan;
8(4).
PMID: 36602878
Although murine models of coronary atherosclerotic disease have been used extensively to determine mechanisms, limited new therapeutic options have emerged. Pigs with familial hypercholesterolemia (FH pigs) develop complex coronary atheromas...
8.
Snarski P, Sukhanov S, Yoshida T, Higashi Y, Danchuk S, Chandrasekar B, et al.
Arterioscler Thromb Vasc Biol
. 2021 Dec;
42(2):113-126.
PMID: 34852642
Objective: IGF-1 (insulin-like growth factor 1) exerts pleiotropic effects including promotion of cellular growth, differentiation, survival, and anabolism. We have shown that systemic IGF-1 administration reduced atherosclerosis in Apoe (apolipoprotein...
9.
Alluri S, Higashi Y, Kil K
Molecules
. 2021 Sep;
26(17).
PMID: 34500609
Chemokines and chemokine receptors have been recognized as critical signal components that maintain the physiological functions of various cells, particularly the immune cells. The signals of chemokines/chemokine receptors guide various...
10.
Okazaki Y, Ichiba T, Higashi Y
BMJ Case Rep
. 2021 Apr;
14(4).
PMID: 33846195
No abstract available.