Yuri Sergeev
Overview
Explore the profile of Yuri Sergeev including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
25
Citations
609
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Chatterjee S, Ghosh S, Sin Z, Davis E, Preval L, Tran N, et al.
bioRxiv
. 2024 Aug;
PMID: 39211129
The retinal pigmented epithelial (RPE) cells maintain retinal homeostasis, and alterations in their function contribute to non-exudative age-related macular degeneration (AMD) . Here, we explore the intricate relationship between RPE...
2.
Ghosh S, Sharma R, Bammidi S, Koontz V, Nemani M, Yazdankhah M, et al.
Nat Commun
. 2024 Jul;
15(1):6150.
PMID: 39034314
Non-neovascular or dry age-related macular degeneration (AMD) is a multi-factorial disease with degeneration of the aging retinal-pigmented epithelium (RPE). Lysosomes play a crucial role in RPE health via phagocytosis and...
3.
Ghosh S, Sharma R, Bammidi S, Koontz V, Nemani M, Yazdankhah M, et al.
bioRxiv
. 2023 Aug;
PMID: 37609254
Age-related macular degeneration (AMD), the leading cause of geriatric blindness, is a multi-factorial disease with retinal-pigmented epithelial (RPE) cell dysfunction as a central pathogenic driver. With RPE degeneration, lysosomal function...
4.
Liu J, He Y, Lwin C, Han M, Guan B, Naik A, et al.
bioRxiv
. 2023 Jun;
PMID: 37333224
Biallelic pathogenic variants in the gene cause a broad spectrum of disorders leading to gait disturbance, visual impairment, anterior hypopituitarism, and hair anomalies. encodes Neuropathy target esterase (NTE), yet the...
5.
Gupta U, Ghosh S, Wallace C, Shang P, Xin Y, Nair A, et al.
Autophagy
. 2022 Apr;
19(1):92-111.
PMID: 35473441
In dry age-related macular degeneration (AMD), LCN2 (lipocalin 2) is upregulated. Whereas LCN2 has been implicated in AMD pathogenesis, the mechanism remains unknown. Here, we report that in retinal pigmented...
6.
Shang P, Stepicheva N, Teel K, McCauley A, Fitting C, Hose S, et al.
Commun Biol
. 2021 Jul;
4(1):850.
PMID: 34239035
The retinal pigmented epithelium (RPE) is a monolayer of multifunctional cells located at the back of the eye. High membrane turnover and polarization, including formation of actin-based apical microvilli, are...
7.
Ghosh S, Liu H, Yazdankhah M, Stepicheva N, Shang P, Vaidya T, et al.
Commun Biol
. 2021 Feb;
4(1):248.
PMID: 33627831
βA3/A1-crystallin, a lens protein that is also expressed in astrocytes, is produced as βA3 and βA1-crystallin isoforms by leaky ribosomal scanning. In a previous human proteome high-throughput array, we found...
8.
Patel M, Sergeev Y
J Anal Pharm Res
. 2021 Jan;
9(3):81-89.
PMID: 33458560
Oculocutaneous albinism type 1 (OCA1) is an autosomal recessive disorder caused by mutations in the tyrosinase gene. OCA1 exists in two forms: OCA1A and OCA1B. OCA1A is caused by a...
9.
Shang P, Valapala M, Grebe R, Hose S, Ghosh S, Bhutto I, et al.
Aging Cell
. 2017 Jan;
16(2):349-359.
PMID: 28083894
The dry (nonneovascular) form of age-related macular degeneration (AMD), a leading cause of blindness in the elderly, has few, if any, treatment options at present. It is characterized by early...
10.
Minegishi Y, Sheng X, Yoshitake K, Sergeev Y, Iejima D, Shibagaki Y, et al.
Sci Rep
. 2016 Sep;
6:33742.
PMID: 27645772
Leber congenital amaurosis (LCA) is a hereditary early-onset retinal dystrophy that is accompanied by severe macular degeneration. In this study, novel compound heterozygous mutations were identified as LCA-causative in chaperonin-containing...