Meysam Yazdankhah
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Explore the profile of Meysam Yazdankhah including associated specialties, affiliations and a list of published articles.
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28
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1549
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Recent Articles
1.
Ghosh S, Sharma R, Bammidi S, Koontz V, Nemani M, Yazdankhah M, et al.
Nat Commun
. 2024 Jul;
15(1):6150.
PMID: 39034314
Non-neovascular or dry age-related macular degeneration (AMD) is a multi-factorial disease with degeneration of the aging retinal-pigmented epithelium (RPE). Lysosomes play a crucial role in RPE health via phagocytosis and...
2.
Yazdankhah M, Ghosh S, Liu H, Hose S, Zigler Jr J, Sinha D
Cells
. 2023 Oct;
12(20.
PMID: 37887340
Mitochondrial dysfunction in astrocytes has been implicated in the development of various neurological disorders. Mitophagy, mitochondrial autophagy, is required for proper mitochondrial function by preventing the accumulation of damaged mitochondria....
3.
Ghosh S, Sharma R, Bammidi S, Koontz V, Nemani M, Yazdankhah M, et al.
bioRxiv
. 2023 Aug;
PMID: 37609254
Age-related macular degeneration (AMD), the leading cause of geriatric blindness, is a multi-factorial disease with retinal-pigmented epithelial (RPE) cell dysfunction as a central pathogenic driver. With RPE degeneration, lysosomal function...
4.
Liu H, Stepicheva N, Ghosh S, Shang P, Chowdhury O, Daley R, et al.
Nat Commun
. 2022 Oct;
13(1):6045.
PMID: 36229454
The retinal pigment epithelium (RPE) plays an important role in the development of diabetic retinopathy (DR), a leading cause of blindness worldwide. Here we set out to explore the role...
5.
Gupta U, Ghosh S, Wallace C, Shang P, Xin Y, Nair A, et al.
Autophagy
. 2022 Apr;
19(1):92-111.
PMID: 35473441
In dry age-related macular degeneration (AMD), LCN2 (lipocalin 2) is upregulated. Whereas LCN2 has been implicated in AMD pathogenesis, the mechanism remains unknown. Here, we report that in retinal pigmented...
6.
Shang P, Stepicheva N, Liu H, Chowdhury O, Franks J, Sun M, et al.
Int J Mol Sci
. 2021 Nov;
22(21).
PMID: 34769409
Degeneration of retinal pigment epithelium (RPE) is one of the most critical phenotypic changes of age-related macular degeneration (AMD), the leading cause of vision loss in the elderly. While cultured...
7.
Shang P, Stepicheva N, Teel K, McCauley A, Fitting C, Hose S, et al.
Commun Biol
. 2021 Jul;
4(1):850.
PMID: 34239035
The retinal pigmented epithelium (RPE) is a monolayer of multifunctional cells located at the back of the eye. High membrane turnover and polarization, including formation of actin-based apical microvilli, are...
8.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy
. 2021 Feb;
17(1):1-382.
PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...
9.
Ghosh S, Liu H, Yazdankhah M, Stepicheva N, Shang P, Vaidya T, et al.
Commun Biol
. 2021 Feb;
4(1):248.
PMID: 33627831
βA3/A1-crystallin, a lens protein that is also expressed in astrocytes, is produced as βA3 and βA1-crystallin isoforms by leaky ribosomal scanning. In a previous human proteome high-throughput array, we found...
10.
Yazdankhah M, Ghosh S, Shang P, Stepicheva N, Hose S, Liu H, et al.
Autophagy
. 2021 Jan;
17(10):3140-3159.
PMID: 33404293
Retinal ganglion cell axons are heavily myelinated (98%) and myelin damage in the optic nerve (ON) severely affects vision. Understanding the molecular mechanism of oligodendrocyte progenitor cell (OPC) differentiation into...