Yunyuan Huang
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Explore the profile of Yunyuan Huang including associated specialties, affiliations and a list of published articles.
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22
Citations
68
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Recent Articles
1.
Mao Z, Liu W, Zou R, Sun L, Huang S, Wu L, et al.
Signal Transduct Target Ther
. 2025 Feb;
10(1):67.
PMID: 39962087
Mitochondrial metabolism-regulated epigenetic modification is a driving force of aging and a promising target for therapeutic intervention. Mitochondrial malate dehydrogenase (MDH2), an enzyme in the TCA cycle, was identified as...
2.
Wei L, Hu Y, Bai L, Xiao C, Liu Z, You Y, et al.
ACS Omega
. 2025 Feb;
10(4):3389-3397.
PMID: 39926536
The reintroduction of the pseudorabies virus (PRV) has led to the emergence of epidemics in some pig farms in China, resulting in significant economic losses. Moreover, the number of human...
3.
Huang Y, Li B, Wu Z, Liu K, Min J
Eur J Med Chem
. 2024 Oct;
280:116965.
PMID: 39413441
PWWP domain-containing proteins play a pivotal role in chromatin-mediated biological processes, and their aberrant regulation is linked to various human diseases. Recent years have witnessed remarkable strides in unraveling the...
4.
Huang Y, Chen X, Yang J, Yao Y, Wang M, Lu T, et al.
J Chem Inf Model
. 2024 Sep;
64(18):7152-7162.
PMID: 39259971
Combination therapy is increasingly favored by pharmaceutical companies and researchers as an effective way to quickly discover new drugs with excellent efficacy, especially in the treatment of complex diseases. Previously,...
5.
Wang J, Liu W, Huang Y, Wang G, Guo X, Shi D, et al.
Adv Sci (Weinh)
. 2024 Jul;
11(36):e2401862.
PMID: 39073681
The pursuit of pharmacological interventions in aging aims focuses on maximizing safety and efficacy, prompting an exploration of natural products endowed with inherent medicinal properties. Subsequently, this work establishes a...
6.
Huang Y, Li Y, Min J
Trends Pharmacol Sci
. 2024 Feb;
45(3):193-196.
PMID: 38341359
The PWWP domain binds to both histone and DNA of a nucleosome in a bivalent way. PWWP domain-containing proteins are involved in different biological processes, and their aberrant expression is...
7.
Wu Z, Huang Y, Liu K, Min J
Biochim Biophys Acta Gene Regul Mech
. 2023 Jun;
1867(1):194952.
PMID: 37263341
Ubiquitination is a fascinating post-translational modification that has received continuous attention since its discovery. In this review, we first provide a concise overview of the E3 ubiquitin ligases, delving into...
8.
Xu Y, Zhang C, Jiang K, Yang X, Chen F, Cheng Z, et al.
Acta Pharm Sin B
. 2023 May;
13(4):1671-1685.
PMID: 37139418
Sodium-glucose cotransporter 2 (SGLT2) inhibitors have been reapproved for heart failure (HF) therapy in patients with and without diabetes. However, the initial glucose-lowering indication of SGLT2i has impeded their uses...
9.
Shi D, Liu W, Gao Y, Li X, Huang Y, Li X, et al.
Nat Aging
. 2023 Apr;
3(3):297-312.
PMID: 37118423
Strategies that can selectively eliminate senescent cells (SnCs), namely senolytics, have been shown to promote healthy lifespan. However, it is challenging to achieve precise, broad-spectrum and tractable senolysis. Here, we...
10.
Extract Exerts Antiaging Effects in Multiple Models and Extends the Lifespan of via DAF-16 and HSF-1
Wang J, Huang Y, Shi K, Bao L, Xiao C, Sun T, et al.
Oxid Med Cell Longev
. 2022 Oct;
2022:3151071.
PMID: 36267808
The development of safe and effective therapeutic interventions is an important issue for delaying aging and reducing the risk of aging-related diseases. Chinese herbal medicines for the treatment of aging...