Yun-Ching Chen
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Explore the profile of Yun-Ching Chen including associated specialties, affiliations and a list of published articles.
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38
Citations
1257
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Recent Articles
1.
Chen Y, Chen A, Hong R, Huang B, Pirooznia M
Sci Rep
. 2024 Dec;
14(1):31382.
PMID: 39733163
The introduction of anti-PD-1/PD-L1 therapies revolutionized treatment for advanced non-small cell lung cancer (NSCLC), yet response rates remain modest, underscoring the need for predictive biomarkers. While a T cell inflamed...
2.
Chen Y, Hsu C, Wang H, Wu S, Chang Y, Chen J, et al.
Cancer Res
. 2024 Nov;
85(3):602-617.
PMID: 39570802
Lung cancer is the most common cause of cancer mortality globally, and the prevalence of lung adenocarcinoma, the most common lung cancer subtype, has increased sharply in East Asia. Early...
3.
Sit W, Cheng M, Chen T, Chen C, Chen B, Huang D, et al.
Gut Microbes
. 2024 Oct;
16(1):2409924.
PMID: 39369445
, a dominant member of the gastric microbiota was associated with various gastrointestinal diseases and presents a significant challenge due to increasing antibiotic resistance. This study identifies 's phospholipase A...
4.
Matthew B, Lebron A, Chen Y, Lohr W, Rollison S, Worthy T, et al.
Ann Am Thorac Soc
. 2023 Mar;
20(7):1073-1076.
PMID: 36930738
No abstract available.
5.
Liu J, Fang W, Yang S, Wu M, Chen T, Chen C, et al.
J Biomed Sci
. 2022 May;
29(1):29.
PMID: 35534851
Background: Castration-resistant prostate cancer (CRPC) with sustained androgen receptor (AR) signaling remains a critical clinical challenge, despite androgen depletion therapy. The Jumonji C-containing histone lysine demethylase family 4 (KDM4) members,...
6.
Sun C, Chen Y, Zurita A, Baptista M, Pittaluga S, Liu D, et al.
Blood Adv
. 2022 Mar;
7(1):145-158.
PMID: 35358998
In chronic lymphocytic leukemia (CLL), B-cell receptor signaling, tumor-microenvironment interactions, and somatic mutations drive disease progression. To better understand the intersection between the microenvironment and molecular events in CLL pathogenesis,...
7.
Xiao W, Ren L, Chen Z, Fang L, Zhao Y, Lack J, et al.
Nat Biotechnol
. 2021 Sep;
39(9):1141-1150.
PMID: 34504346
Clinical applications of precision oncology require accurate tests that can distinguish true cancer-specific mutations from errors introduced at each step of next-generation sequencing (NGS). To date, no bulk sequencing study...
8.
Jones W, Gong B, Novoradovskaya N, Li D, Kusko R, Richmond T, et al.
Genome Biol
. 2021 Apr;
22(1):111.
PMID: 33863366
Background: Oncopanel genomic testing, which identifies important somatic variants, is increasingly common in medical practice and especially in clinical trials. Currently, there is a paucity of reliable genomic reference samples...
9.
Singh K, Chen Y, Hassanzadeh S, Han K, Judy J, Seifuddin F, et al.
Front Genet
. 2021 Apr;
12:599261.
PMID: 33796130
Analyzing host cells' transcriptional response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection will help delineate biological processes underlying viral pathogenesis. First, analysis of expression profiles of lung cell...
10.
Matthew B, Hasani A, Chen Y, Pirooznia M, Stylianou M, Rollison S, et al.
Chest
. 2021 Feb;
160(1):199-208.
PMID: 33549601
Background: Lymphangioleiomyomatosis (LAM) is a rare lung disease found primarily in women of childbearing age, characterized by the formation of air-filled cysts, which may be associated with reductions in lung...