Fayaz Seifuddin
Overview
Explore the profile of Fayaz Seifuddin including associated specialties, affiliations and a list of published articles.
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Articles
41
Citations
776
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Recent Articles
1.
Cox O, Seifuddin F, Guo J, Pirooznia M, Boersma G, Wang J, et al.
Epigenetics
. 2024 Sep;
19(1):2393945.
PMID: 39306700
Epigenomic annotations for the rat lag far behind those of human and mouse, despite the rat's immense utility in pharmacological and behavioral studies and the need to understand their epigenetic...
2.
Eachus H, Oberski L, Paveley J, Bacila I, Ashton J, Esposito U, et al.
Dis Model Mech
. 2023 Aug;
16(9).
PMID: 37525888
Glucocorticoid resistance is commonly observed in depression, and has been linked to reduced expression and/or function of the glucocorticoid receptor (NR3C1 in human, hereafter referred to as GR). Previous studies...
3.
Brusca S, Elinoff J, Zou Y, Jang M, Kong H, Demirkale C, et al.
Circulation
. 2022 Aug;
146(14):1033-1045.
PMID: 36004627
Background: Cell-free DNA (cfDNA) is a noninvasive marker of cellular injury. Its significance in pulmonary arterial hypertension (PAH) is unknown. Methods: Plasma cfDNA was measured in 2 PAH cohorts (A,...
4.
Zandi P, Jaffe A, Goes F, Burke E, Collado-Torres L, Huuki-Myers L, et al.
Nat Neurosci
. 2022 Mar;
25(3):381-389.
PMID: 35260864
Recent genetic studies have identified variants associated with bipolar disorder (BD), but it remains unclear how brain gene expression is altered in BD and how genetic risk for BD may...
5.
Andargie T, Zhou W, Karaba A, Li T, Seifuddin F, Rittenhouse A, et al.
Res Sq
. 2022 Jan;
PMID: 35075453
COVID-19 pathogenesis is associated with an exuberant inflammatory response. However, the tissue injury pattern and immune response in solid-organ transplant recipients (SOTRs) taking immunosuppressive therapy have not been well characterized....
6.
Bhat D, Olkhanud P, Gangaplara A, Seifuddin F, Pirooznia M, Biancotto A, et al.
Front Immunol
. 2021 Dec;
12:757279.
PMID: 34917079
Haploidentical hematopoietic stem cell transplantation (haplo-HSCT) is a widely available curative option for patients with sickle cell disease (SCD). Our original non-myeloablative haplo-HSCT trial employing post-transplant (PT) cyclophosphamide had a...
7.
Xiao W, Ren L, Chen Z, Fang L, Zhao Y, Lack J, et al.
Nat Biotechnol
. 2021 Sep;
39(9):1141-1150.
PMID: 34504346
Clinical applications of precision oncology require accurate tests that can distinguish true cancer-specific mutations from errors introduced at each step of next-generation sequencing (NGS). To date, no bulk sequencing study...
8.
Araki D, Fu J, Huntsman H, Cordes S, Seifuddin F, Alvarado L, et al.
Stem Cell Reports
. 2021 Aug;
16(9):2336-2350.
PMID: 34450041
Activation of NOTCH signaling in human hematopoietic stem/progenitor cells (HSPCs) by treatment with an engineered Delta-like ligand (DELTA1 [DXI]) has enabled ex vivo expansion of short-term HSPCs, but the effect...
9.
Lee R, Zandi P, Lin Y, Seifuddin F, Benke K, McCaul M, et al.
Stress
. 2021 Jul;
24(6):840-848.
PMID: 34279166
Allostatic load (AL) refers to the cumulative "wear and tear" on an organism throughout its lifetime. One of the primary contributing factors to AL is prolonged exposure to stress or...
10.
Singh K, Chen Y, Hassanzadeh S, Han K, Judy J, Seifuddin F, et al.
Front Genet
. 2021 Apr;
12:599261.
PMID: 33796130
Analyzing host cells' transcriptional response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection will help delineate biological processes underlying viral pathogenesis. First, analysis of expression profiles of lung cell...