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Yujun Pei

Explore the profile of Yujun Pei including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 166
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Recent Articles
1.
Deng Y, Qiao Z, Zhou C, Pei Y, Xu H, Kang X, et al.
Cells . 2024 Oct; 13(19. PMID: 39404399
Brain endothelial cells (ECs) are essential elements of the blood-brain barrier (BBB), maintaining its integrity through both paracellular junctions and transcellular transport systems. Myosin IIA, a multifunctional protein, plays a...
2.
Li H, Du Y, Cheng K, Chen Y, Wei L, Pei Y, et al.
Cell Discov . 2024 Aug; 10(1):89. PMID: 39187483
High myopia (HM) is a leading cause of blindness worldwide with currently no effective interventions available. A major hurdle lies in its often isolated perception as a purely ocular morbidity,...
3.
Pei Y, Xiang Z, Wen K, Tu C, Wang X, Zhang Y, et al.
Front Immunol . 2022 Jul; 13:872122. PMID: 35784354
Although γδ-T cell-based tumor immunotherapy using phosphoantigens to boost γδ-T cell immunity has shown success in some cancer patients, the clinical application is limited due to the rapid exhaustion of...
4.
Wang X, Xiang Z, Liu Y, Huang C, Pei Y, Wang X, et al.
Sci Transl Med . 2020 Oct; 12(563). PMID: 32998970
Treatment of life-threatening Epstein-Barr virus (EBV)-associated tumors remains a great challenge, especially for patients with relapsed or refractory disease. Here, we found that exosomes derived from phosphoantigen-expanded Vδ2-T cells (Vδ2-T-Exos)...
5.
Pei Y, Wen K, Xiang Z, Huang C, Wang X, Mu X, et al.
Signal Transduct Target Ther . 2020 Jun; 5(1):74. PMID: 32488072
Influenza epidemics and pandemics are constant threats to global public health. Although strategies including vaccines and antiviral drugs have achieved great advances in controlling influenza virus infection, the efficacy of...
6.
Cao J, Zhao M, Liu J, Zhang X, Pei Y, Wang J, et al.
Theranostics . 2019 Feb; 9(3):811-828. PMID: 30809310
Targeting cancer stem cells (CSCs) has been proposed as a new strategy to eradicate malignancies, including hepatocellular carcinoma (HCC). However, the mechanisms by which CSCs sustain their self-renewal and chemoresistance...
7.
Cheng Q, Liu J, Pei Y, Zhang Y, Zhou D, Pan W, et al.
PLoS Pathog . 2018 Nov; 14(11):e1007440. PMID: 30462731
CD4+ T cells play predominant roles in protective immunity against blood-stage Plasmodium infection, both for IFN-γ-dependent effector mechanisms and providing B cell helper signals. Neddylation, an ubiquitination-like process triggered by...
8.
Cao H, Xie J, Guo L, Han K, Pei Y, Li X, et al.
Leuk Lymphoma . 2017 Aug; 59(5):1222-1230. PMID: 28849722
All-trans retinoic acid (ATRA) has demonstrated notable success in the treatment of acute promyelocytic leukemia (APL) by inducing granulocytic differentiation. The underlying mechanisms of ATRA therapeutic effects have not been...
9.
Qiu G, Liu J, Cheng Q, Wang Q, Jing Z, Pei Y, et al.
Front Immunol . 2017 Jun; 8:575. PMID: 28572806
Autophagy plays a central role in maintaining T cell homeostasis. Our previous study has shown that hepatocyte-specific deficiency of receptor for activated C kinase 1 (RACK1) leads to lipid accumulation...
10.
Zhang X, Ye Z, Pei Y, Qiu G, Wang Q, Xu Y, et al.
Cell Mol Immunol . 2016 Sep; 13(5):578-83. PMID: 27593482
Type I interferons such as interferon-beta (IFN-β) play essential roles in the host innate immune response to herpes simplex virus type I (HSV-1) infection. The transcription of type I interferon...