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Yuji Matsuya

Explore the profile of Yuji Matsuya including associated specialties, affiliations and a list of published articles. Areas
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Articles 60
Citations 345
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Recent Articles
1.
Tanioka M, Enomoto F, Kitamura F, Nakamura R, Takano A, Kanayama S, et al.
J Org Chem . 2025 Mar; 90(10):3610-3614. PMID: 40025701
Ligation reactions that proceed at room temperature under aqueous conditions and without catalysts are in high demand, including bioorthogonal reactions. We report a mild amide-ligation reaction of iminophosphoranes with -difluoroalkenes....
2.
Tanioka M, Kanayama S, Kitamura F, Takano A, Ikeda Y, Kohyama A, et al.
J Org Chem . 2025 Jan; 90(4):1501-1506. PMID: 39801043
The development of bioorthogonal reactions is expected to propel further advances in chemical biology. In this study, we demonstrate Staudinger-Diels-Alder (SDA) ligation as a candidate for a new bioorthogonal reaction....
3.
Tanioka M, Mori M, Harada M, Matsuya Y, Kamino S
Chem Commun (Camb) . 2024 Jun; 60(50):6407-6410. PMID: 38828530
Polarity-responsive luminophores (PRLs), whose emission properties change in response to the polarity of the surrounding environment, are used for the fluorescence sensing of intracellular environments and various chemical compounds. Herein,...
4.
Tanioka M, Oyama M, Nakajima K, Mori M, Harada M, Matsuya Y, et al.
Phys Chem Chem Phys . 2024 Jan; 26(5):4474-4479. PMID: 38240132
The recent expansion of photoredox catalysis into chemical biology has underscored the importance of photochemistry, attracting the attention of many researchers. On the other hand, as conventional photoredox catalysts were...
5.
Kohyama A, Shiuchi A, Zhou Y, Tanioka M, Sugimoto K, Sakurai H, et al.
Org Biomol Chem . 2023 May; 21(22):4656-4660. PMID: 37212260
Tuning the electrophilicities of Michael acceptors is important for the development of targeted covalent drugs. To this end, the electronic effects of electrophilic structures have been well investigated, but not...
6.
Kosuge S, Araki Y, Tsuge K, Sugimoto K, Matsuya Y
J Org Chem . 2023 May; 88(11):6973-6986. PMID: 37191633
The one-pot de novo synthesis of pentasubstituted pyridines was realized following the process of Au(I)-autotandem catalysis and subsequent aromatization. The process involves aza-enyne metathesis with aryl propiolates to yield 1-azabutadienes...
7.
Kikuchi S, Wada A, Kamihara Y, Okazaki K, Jawaid P, Rehman M, et al.
Cells . 2023 Apr; 12(7). PMID: 37048172
DPP8/9 inhibition induces either pyroptotic or apoptotic cell death in hematological malignancies. We previously reported that treatment with the DPP8/9 inhibitor 1G244 resulted in apoptotic cell death in myeloma, and...
8.
Kohyama A, Kim M, Yokoyama R, Sun S, Omar A, Phan N, et al.
Bioorg Med Chem . 2021 Dec; 54:116563. PMID: 34942553
Pancreatic cancer is one of the deadliest types of malignancies. A new intervention aiming to combat pancreatic cancer is targeting its extra-ordinary ability to tolerate nutrition starvation, a phenomenon known...
9.
Fujii T, Sugimoto K, Noda T, Shimizu T, Matsuya Y, Sakai H
Biochem Biophys Res Commun . 2021 Jun; 567:177-182. PMID: 34166915
The gastric proton pump (H,K-ATPase) responsible for the H secretion of gastric acid is an essential therapeutic target for acid-related diseases. H,K-ATPase belongs to a P-type ATPase family. Here, we...
10.
Abdellatef A, Zhou Y, Yamada A, Elmekkawy S, Kohyama A, Yokoyama S, et al.
Biomed Pharmacother . 2021 May; 140:111737. PMID: 34020249
Guggulsterone (GS) [4,17(20)-pregnadiene-3,16-dione], is the main active phytosterol constituent in guggul, the gum resin of Commiphora wightii (Arnott.) Bhand./Commiphora mukul Engl. tree, and is known for its medicinal effects. In...