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Yousef M O Alhammad

Explore the profile of Yousef M O Alhammad including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 296
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Recent Articles
1.
Alaql F, Alhafufi A, Kasem S, Alhammad Y, Albaqshi H, Alyousaf A, et al.
Animals (Basel) . 2022 Oct; 12(19). PMID: 36230462
Equine influenza is a major cause of respiratory infections in horses and can spread rapidly despite the availability of commercial vaccines. This study aimed to screen the incidence of equine...
2.
Dasovich M, Zhuo J, Goodman J, Thomas A, McPherson R, Jayabalan A, et al.
ACS Chem Biol . 2021 Dec; 17(1):17-23. PMID: 34904435
Macrodomains are a class of conserved ADP-ribosylhydrolases expressed by viruses of pandemic concern, including coronaviruses and alphaviruses. Viral macrodomains are critical for replication and virus-induced pathogenesis; therefore, these enzymes are...
3.
Alhammad Y, Kashipathy M, Roy A, Gagne J, McDonald P, Gao P, et al.
J Virol . 2020 Nov; 95(3). PMID: 33158944
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other SARS-related CoVs encode 3 tandem macrodomains within nonstructural protein 3 (nsp3). The first macrodomain, Mac1, is conserved throughout CoVs and binds...
4.
Heer C, Sanderson D, Voth L, Alhammad Y, Schmidt M, Trammell S, et al.
J Biol Chem . 2020 Oct; 295(52):17986-17996. PMID: 33051211
Poly(ADP-ribose) polymerase (PARP) superfamily members covalently link either a single ADP-ribose (ADPR) or a chain of ADPR units to proteins using NAD as the source of ADPR. Although the well-known...
5.
Alhammad Y, Kashipathy M, Roy A, Gagne J, McDonald P, Gao P, et al.
bioRxiv . 2020 Jun; PMID: 32511412
Importance: SARS-CoV-2 has recently emerged into the human population and has led to a worldwide pandemic of COVID-19 that has caused greater than 900 thousand deaths worldwide. With, no currently...
6.
Heer C, Sanderson D, Voth L, Alhammad Y, Schmidt M, Trammell S, et al.
bioRxiv . 2020 Jun; PMID: 32511303
Poly-ADP-ribose polymerase (PARP) superfamily members covalently link either a single ADP-ribose (ADPR) or a chain of ADPR units to proteins using nicotinamide adenine dinucleotide (NAD) as the source of ADPR....
7.
Alhammad Y, Fehr A
Viruses . 2020 Apr; 12(4). PMID: 32244383
Macrodomains, enzymes that remove ADP-ribose from proteins, are encoded by several families of RNA viruses and have recently been shown to counter innate immune responses to virus infection. ADP-ribose is...
8.
Al-Ghadeer H, Chu D, Rihan E, Abd-Allah E, Gu H, Chin A, et al.
Emerg Infect Dis . 2018 Jun; 24(10):1961-1964. PMID: 29943727
Highly pathogenic avian influenza A(H5N8) viruses have been detected in several continents. However, limited viral sequence data are available from countries in the Middle East. We report full-genome analyses of...
9.
Alhammad Y, Maharajh S, Butcher R, Eden J, White P, Poumbourios P, et al.
PLoS One . 2015 May; 10(5):e0126397. PMID: 25970466
The E2 glycoprotein of Hepatitis C virus (HCV) is a major target of the neutralizing antibody (NAb) response with the majority of epitopes located within its receptor binding domain (RBD;...