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Yoshitaka Ohno

Explore the profile of Yoshitaka Ohno including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 384
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Recent Articles
1.
Ohno Y, Nakatani M, Matsui Y, Suda Y, Ito T, Ando K, et al.
In Vivo . 2024 Dec; 39(1):218-227. PMID: 39740887
Background/aim: Lactate is a physiologically active substance secreted by skeletal muscle that has been suggested to stimulate muscle mass gain. However, the molecular mechanism for lactate-associated muscle hypertrophy remains unclear....
2.
Ohno Y, Toshino M, Mohammed A, Fujiwara Y, Komohara Y, Onodera R, et al.
Carbohydr Polym . 2023 Feb; 305:120551. PMID: 36737200
Methylated β-cyclodextrin (MβCD) can extract cholesterol from lipid rafts and induce apoptosis in cancer cells by inhibiting activation of the PI3K-Akt-Bad pathway. In this study, we modified MβCD with mannose...
3.
Hayashi T, Nakagawa F, Ohno Y, Suzuki Y, Ishiki H, Onodera R, et al.
Eur J Pharm Biopharm . 2022 Nov; 181:113-121. PMID: 36372270
Recent viral pandemics have increased global demand for vaccines. However, the supply of effective and safe vaccine not only to developed countries but also developing countries with inadequate storage equipment...
4.
Hassan M, Mohammed A, Elamin K, Devkota H, Ohno Y, Motoyama K, et al.
Chem Pharm Bull (Tokyo) . 2020 Nov; 68(11):1117-1120. PMID: 33132380
Zerumbone is a multifunctional compound which shows various biological activities, such as antitumor activity, anti-inflammatory activity, antiulcer activity, etc. However, to use Zerumbone as functional foods or medicines, its pharmaceutical...
5.
Yokoyama R, Taharabaru T, Nishida T, Ohno Y, Maeda Y, Sato M, et al.
J Control Release . 2020 Oct; 328:722-735. PMID: 33002523
The blood-brain barrier (BBB) prevents the permeability of drugs into the brain, and as such limits the management of various brain diseases. To overcome this barrier, drug-encapsulating nanoparticles or vesicles,...
6.
Yokoyama S, Ohno Y, Egawa T, Ohashi K, Ito R, Ortuste Quiroga H, et al.
Int J Mol Sci . 2020 Sep; 21(17). PMID: 32887414
We explored the interrelationship between a tissue-specific alternative splicing factor muscleblind-like 1 (MBNL1) and peroxisome proliferator-activated receptor-γ coactivator 1-α (PGC-1α), B-cell lymphoma 2 (Bcl-2) or Bcl-2-associated X protein (Bax) in...
7.
Egawa T, Ohno Y, Yokoyama S, Yokokawa T, Tsuda S, Goto K, et al.
Foods . 2019 Sep; 8(10). PMID: 31557885
We investigated the protective effect of Brazilian propolis, a natural resinous substance produced by honeybees, against glycation stress in mouse skeletal muscles. Mice were divided into four groups: (1) Normal...
8.
Ohno Y, Ando K, Ito T, Suda Y, Matsui Y, Oyama A, et al.
Nutrients . 2019 Apr; 11(4). PMID: 30999708
The effects of lactate on muscle mass and regeneration were investigated using mouse skeletal muscle tissue and cultured C2C12 cells. Male C57BL/6J mice were randomly divided into (1) control, (2)...
9.
Hayashi T, Momota M, Kuroda E, Kusakabe T, Kobari S, Makisaka K, et al.
Front Immunol . 2018 Dec; 9:2619. PMID: 30515151
Recently, it was reported that 2-hydroxypropyl-β-cyclodextrin (HP-β-CyD), a common pharmaceutical additive, can act as a vaccine adjuvant to enhance protective type-2 immunogenicity to co-administered seasonal influenza split vaccine by inducing...
10.
Ito R, Higa M, Goto A, Aoshima M, Ikuta A, Ohashi K, et al.
PLoS One . 2018 Oct; 13(10):e0205645. PMID: 30308063
This study investigated the effects of AdipoRon, which is an agonist for adiponectin receptor 1 (AdipoR1) and AdipoR2, on the protein content, myotube diameter, and number of nuclei per myotube...