Yoshihiro Toya
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Explore the profile of Yoshihiro Toya including associated specialties, affiliations and a list of published articles.
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68
Citations
763
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Recent Articles
1.
Nishiguchi H, Niide T, Toya Y, Shimizu H
Biosci Biotechnol Biochem
. 2025 Feb;
PMID: 39900468
Phosphoribulokinase (PRK) is a key enzyme in the Calvin cycle of cyanobacteria required for CO2 fixation and enhancing intracellular PRK activity will contribute to altering the metabolic state. In Synechocystis...
2.
Toya Y, Imada T, Ishibashi M, Kawamoto Y, Kawamoto Y, Isshiki K, et al.
FEMS Microbiol Lett
. 2025 Jan;
372.
PMID: 39870377
Phosphoenolpyruvate carboxylase encoded by ppc catalyzes the anaplerotic reaction of oxaloacetate in the tricarboxylic acid (TCA) cycle in Escherichia coli. Deletion of ppc does not prevent the cells from replenishing...
3.
C-metabolic flux analysis of respiratory chain disrupted strain ΔndhF1 of Synechocystis sp. PCC 6803
Wada K, Toya Y, Matsuda F, Shimizu H
Appl Biochem Biotechnol
. 2025 Jan;
PMID: 39812922
Cyanobacteria are advantageous hosts for industrial applications toward achieving sustainable society due to their unique and superior properties such as atmospheric CO fixation via photosynthesis. However, cyanobacterial productivities tend to...
4.
Ueno K, Sawada S, Ishibashi M, Kanda Y, Shimizu H, Toya Y
J Bacteriol
. 2024 Oct;
206(11):e0027624.
PMID: 39387572
NADPH is a redox cofactor that drives the anabolic reactions. Although major NADPH generation reactions have been identified in , some minor reactions have not been identified. In the present...
5.
Hirose Y, Zielinski D, Poudel S, Rychel K, Baker J, Toya Y, et al.
mSystems
. 2024 Aug;
9(9):e0073624.
PMID: 39158303
is responsible for a range of diseases in humans contributing significantly to morbidity and mortality. Among more than 200 serotypes of , serotype M1 strains hold the greatest clinical relevance...
6.
Mori H, Matsui M, Bamba T, Hori Y, Kitamura S, Toya Y, et al.
Metab Eng
. 2024 Jul;
84:180-190.
PMID: 38969164
Glutathione is a tripeptide of excellent value in the pharmaceutical, food, and cosmetic industries that is currently produced during yeast fermentation. In this case, glutathione accumulates intracellularly, which hinders high...
7.
Toya Y, Shimizu H
Curr Opin Biotechnol
. 2024 Apr;
87:103133.
PMID: 38640846
Microbial fermentation employs two strategies: growth- and nongrowth-coupled productions. Stoichiometric metabolic models with flux balance analysis enable pathway engineering to couple target synthesis with growth, yielding numerous successful results. Growth-coupled...
8.
Matsuyama C, Seike T, Okahashi N, Niide T, Hara K, Hirono-Hara Y, et al.
J Biosci Bioeng
. 2024 Jan;
137(3):187-194.
PMID: 38281859
Overexpression of proteins by introducing a DNA vector is among the most important tools for the metabolic engineering of microorganisms such as Escherichia coli. Protein overexpression imposes a burden on...
9.
Akagi H, Shimizu H, Toya Y
Biotechnol Bioeng
. 2023 Dec;
121(3):1016-1025.
PMID: 38116710
Optogenetics is an attractive synthetic biology tool for controlling the metabolic flux distribution. Here, we demonstrated optogenetic flux ratio control of glycolytic pathways consisting of the Embden-Meyerhof-Parnas (EMP), pentose phosphate...
10.
Wada K, Uebayashi K, Toya Y, Putri S, Matsuda F, Fukusaki E, et al.
J Gen Appl Microbiol
. 2023 Mar;
69(4):185-195.
PMID: 36935115
Although n-butanol (BuOH) is an ideal fuel because of its superior physical properties, it has toxicity to microbes. Previously, a Synechococcus elongatus PCC 7942 derivative strain that produces BuOH from...