Yoon Kyung Jo
Overview
Explore the profile of Yoon Kyung Jo including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
639
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Recent Articles
1.
Shin Y, Sa J, Lee Y, Kim D, Chang N, Cho H, et al.
J Exp Med
. 2019 Mar;
216(5):1120-1134.
PMID: 30898893
Glioblastoma GBM is the most malignant brain tumor with profound genomic alterations. Tumor suppressor genes regulate multiple signaling networks that restrict cellular proliferation and present barriers to malignant transformation. While...
2.
Shin J, Park S, Jo D, Park N, Kim J, Bae J, et al.
Autophagy
. 2019 Mar;
15(9):1495-1505.
PMID: 30821607
Several studies have shown that dysfunction of macroautophagy/autophagy is associated with many human diseases, including neurodegenerative disease and cancer. To explore the molecular mechanisms of autophagy, we performed a cell-based...
3.
Jo Y, Park N, Shin J, Jo D, Bae J, Choi E, et al.
Anticancer Res
. 2017 Dec;
38(1):271-277.
PMID: 29277783
The ultraviolent irradiation resistance-associated gene (UVRAG), a component of the Beclin 1/autophagy-related 6 complex, regulates the autophagy initiation step and functions in the DNA-damage response. UVRAG is frequently mutated in...
4.
Lee H, Tak H, Park S, Jo Y, Cho D, Lee E
BMB Rep
. 2017 Feb;
50(4):214-219.
PMID: 28148392
Mitochondria play pivotal roles in the ATP production, apoptosis and generation of reactive oxygen species. Although dynamic regulation of mitochondria morphology is a critical step to maintain cellular homeostasis, the...
5.
Choi H, Shin J, Kim E, Park S, Bae I, Jo Y, et al.
PLoS One
. 2016 Dec;
11(12):e0168025.
PMID: 27941997
The primary cilium is an organelle protruding from the cell body that senses external stimuli including chemical, mechanical, light, osmotic, fluid flow, and gravitational signals. Skin is always exposed to...
6.
Jo Y, Roh S, Lee H, Park N, Choi E, Oh J, et al.
Cancer Lett
. 2016 Nov;
385:21-27.
PMID: 27836735
Autophagy plays complex roles in tumor initiation and development, and the expression of autophagy-related genes (ATGs) is differentially regulated in various cancer cells, depending on their environment. In this study,...
7.
Park S, Jo D, Jo S, Shin D, Shim S, Jo Y, et al.
Oncotarget
. 2016 Sep;
7(40):65957-65967.
PMID: 27602754
The tumor necrosis factor-related apoptosis inducing ligand (TRAIL) preferentially induces apoptosis in cancer cells. However, many tumors are resistant to TRAIL-induced apoptosis, and resistance mechanisms are not fully understood. To...
8.
Jo Y, Park N, Park S, Kim B, Shin J, Jo D, et al.
Oncotarget
. 2016 Aug;
7(35):57186-57196.
PMID: 27527864
Autophagy is a catabolic degradation process and maintains cellular homeostasis. And autophagy is activated in response to various stress conditions. Although O-GlcNAcylation functions a sensor for nutrient and stress, the...
9.
Park S, Lee H, Jo D, Jo Y, Shin J, Kim H, et al.
Biochim Biophys Acta
. 2015 Nov;
1849(12):1423-31.
PMID: 26518267
Excessive mitochondrial fission is associated with the pathogenesis of neurodegenerative diseases. Dynamin-related protein 1 (Drp1) possesses specific fission activity in the mitochondria and peroxisomes. Various post-translational modifications of Drp1 are...
10.
Shin J, Bae D, Kim E, Kim H, Park S, Jo Y, et al.
Biomol Ther (Seoul)
. 2015 Jul;
23(4):327-32.
PMID: 26157548
Primary cilia have critical roles in coordinating multiple cellular signaling pathways. Dysregulation of primary cilia is implicated in various ciliopathies. To identify specific regulators of autophagy, we screened chemical libraries...