Doo Sin Jo
Overview
Explore the profile of Doo Sin Jo including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
557
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Recent Articles
1.
Kim Y, Kim J, Bae J, Park N, Kim S, Park D, et al.
Bioorg Med Chem Lett
. 2025 Feb;
120:130130.
PMID: 39923905
Autophagy-mediated organelle quality control is vital for cellular homeostasis. However, the mechanisms underlying selective autophagy of peroxisomes, known as pexophagy, are less well understood than those of other organelles, such...
2.
Park N, Jo D, Yang J, Bae J, Kim J, Kim Y, et al.
Nat Commun
. 2025 Jan;
16(1):1109.
PMID: 39875384
Lysophagy eliminates damaged lysosomes and is crucial to cellular homeostasis; however, its underlying mechanisms are not entirely understood. We screen a ubiquitination-related compound library and determine that the substrate recognition...
3.
Park N, Jo D, Park H, Bae J, Kim Y, Kim J, et al.
Autophagy
. 2024 Oct;
21(3):664-673.
PMID: 39477686
Melanosomes play a pivotal role in skin color and photoprotection. In contrast to the well-elucidated pathway of melanosome biogenesis, the process of melanosome degradation, referred to as melanophagy, is largely...
4.
Kim J, Hyung H, Bae J, Jang S, Park N, Jo D, et al.
BMB Rep
. 2024 Jul;
57(10):453-458.
PMID: 39044457
Primary cilia are crucial for cellular balance, serving as sensors for external conditions. Nephronophthisis and related ciliopathies, which are hereditary and degenerative, stem from genetic mutations in cilia-related genes. However,...
5.
Kim Y, Park N, Jo D, Bae J, Kim J, Park K, et al.
Molecules
. 2024 Jan;
29(2).
PMID: 38257395
Autophagy is a pivotal biological process responsible for maintaining the homeostasis of intracellular organelles. Yet the molecular intricacies of peroxisomal autophagy (pexophagy) remain largely elusive. From a ubiquitin-related chemical library...
6.
Bae J, Jang S, Kim J, Hyung H, Park N, Kim Y, et al.
Mol Brain
. 2023 May;
16(1):41.
PMID: 37170364
The primary cilium, an antenna-like structure on the cell surface, acts as a mechanical and chemical sensory organelle. Primary cilia play critical roles in sensing the extracellular environment to coordinate...
7.
Silwal P, Kim Y, Lee Y, Kim I, Jeon S, Roh T, et al.
Exp Mol Med
. 2023 Jan;
55(2):333-346.
PMID: 36720915
The Arg/N-degron pathway, which is involved in the degradation of proteins bearing an N-terminal signal peptide, is connected to p62/SQSTM1-mediated autophagy. However, the impact of the molecular link between the...
8.
Lee H, Kim S, Kim Y, Kim S, Oh G, Bae J, et al.
Cells
. 2023 Jan;
12(1).
PMID: 36611940
Selective autophagy controls cellular homeostasis by degrading unnecessary or damaged cellular components. Melanosomes are specialized organelles that regulate the biogenesis, storage, and transport of melanin in melanocytes. However, the mechanisms...
9.
Demers N, Riccio V, Jo D, Bhandari S, Law K, Liao W, et al.
Autophagy
. 2022 Dec;
19(6):1781-1802.
PMID: 36541703
Peroxisomes are rapidly degraded during amino acid and oxygen deprivation by a type of selective autophagy called pexophagy. However, how damaged peroxisomes are detected and removed from the cell is...
10.
Kim Y, Jo D, Park N, Bae J, Kim J, Lee H, et al.
Cells
. 2022 Sep;
11(18).
PMID: 36139416
Although autophagy regulates the quality and quantity of cellular compartments, the regulatory mechanisms underlying peroxisomal autophagy (pexophagy) remain largely unknown. In this study, we identified several BRD4 inhibitors, including molibresib,...