Yong-Xing Tang
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Explore the profile of Yong-Xing Tang including associated specialties, affiliations and a list of published articles.
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9
Citations
2
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Recent Articles
1.
Iodine as Polarity-Reversal Catalyst: Synthesis of a Fused Heterocycle with Contiguous Stereocenters
Wang L, Song Y, Zhou Y, Tang Y, Wu C, Yu Z, et al.
Org Lett
. 2024 Dec;
27(1):91-96.
PMID: 39704482
We report an unconventional I-catalyzed cascade reaction for the synthesis of angular triquinane derivatives with a fused heterocycle skeleton, leveraging enaminones and anilines as simple acyclic precursors. The key to...
2.
Wu C, Chen X, Yang D, Tang Y, Wang L, Du Y, et al.
Org Lett
. 2024 Sep;
26(40):8589-8593.
PMID: 39329447
A three-component annulation reaction and trifluoromethylation for the construction of 3-(trifluoromethyl)-4-pyrans using β-CF-1,3-enynes, BrCFCOEt, and sulfoxonium ylides as readily available substrates has been developed. This metal-free process involves two C-F...
3.
Tang Y, Zhou Y, Wu H, Wang L, Wu C, Zhuang S, et al.
Chem Commun (Camb)
. 2024 Jun;
60(56):7180-7183.
PMID: 38904415
A novel process using -benzylhydroxylamine hydrochloride as a "C1N1 synthon" in [2+2+1] cyclization for the construction of 1,2,5-trisubstituted imidazoles has been described for the first time. The key to realizing...
4.
Ma L, Zhou Y, Tang Y, Chen T, Wang Z, Wu Y, et al.
J Org Chem
. 2024 Feb;
89(6):3941-3953.
PMID: 38421294
An efficient synthetic method for constructing 2,3- and 2,4-disubstituted pyrimidio[1,2-]indazole skeletons through I-DMSO-mediated and substrate-controlled regioselective [4 + 2] cyclization is reported. The reaction conditions are mild, its operation is...
5.
Liu J, Zhuang S, Tang Y, Chen X, Zhou Y, Wu Y, et al.
J Org Chem
. 2023 Aug;
88(16):12000-12012.
PMID: 37540765
An I-DMSO-mediated multicomponent [3+1+2] cascade annulation reaction using aryl methyl ketones, enaminones, and benzo[]isoxazol-3-amine as substrates has been developed. This metal-free reaction involved the transannulation of benzo[]isoxazol-3-amines with the formation...
6.
Zhuang S, Liu J, Guo H, Tang Y, Chen X, Ma J, et al.
Org Lett
. 2022 Nov;
24(46):8573-8577.
PMID: 36378685
An I-DMSO mediated multicomponent [3+2] cascade annulation reaction using methyl ketones, 1,2,3,4-tetrahydroisoquinolines (THIQ) and cyclopropenones as readily available substrates has been developed. This metal-free process involves N-H/α-C(sp)-H trifunctionalization of THIQ...
7.
Zhuang S, Tang Y, Liu J, Chen X, Ma J, Wu Y, et al.
Org Lett
. 2022 Apr;
24(15):2858-2862.
PMID: 35394795
An I-DMSO-mediated cascade reaction using methyl ketones and 1,2,3,4-tetrahydroisoquinolines (THIQs) as commercially available substrates has been developed for the construction of pyrrolo[2,1-]isoquinoline derivatives. This metal-free process involves N-H/α-C(sp)-H difunctionalization of...
8.
Zhuang S, Tang Y, Chen X, Wu Y, Wu A
J Org Chem
. 2021 Nov;
86(23):17101-17109.
PMID: 34739234
A copper-catalyzed oxidative C(sp)-H/C(sp)-H cross-coupling reaction of methyl ketones and 3-methylbenzo[]isoxazoles has been developed for the direct synthesis of 3-oxoindolin-2-ylidene derivatives. This process involves an intermolecular nucleophilic addition/ring-opening/aza-Michael addition cascade,...
9.
Zhuang S, Tang Y, Chen X, Wu Y, Wu A
Org Biomol Chem
. 2021 Apr;
19(19):4258-4262.
PMID: 33890609
An I-DMSO mediated oxidative amidation of methyl ketones using anthranils as masked N-nucleophiles has been developed for the direct synthesis of α-ketoamides with high atom-economy. This metal-free process involves reductive...