Yong-Chuan Wong
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Explore the profile of Yong-Chuan Wong including associated specialties, affiliations and a list of published articles.
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36
Citations
946
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Recent Articles
1.
Chiu Y, Liu J, Tang K, Wong Y, Khanna K, Ling M
PLoS One
. 2012 Dec;
7(12):e51108.
PMID: 23272087
The ATM/ATR DNA damage checkpoint functions in the maintenance of genetic stability and some missense variants of the ATM gene have been shown to confer a moderate increased risk of...
2.
Liang D, Qin Y, Zhao W, Zhai X, Guo Z, Wang R, et al.
Cancer Lett
. 2011 Jul;
310(1):69-76.
PMID: 21794975
S-allylmercaptocysteine (SAMC), one of the water-soluble organosulfur garlic derivatives, has been demonstrated as a suppressive agent against some tumors. The effects of SAMC on the proliferation and metastasis of colorectal...
3.
Luk S, Lee T, Liu J, Lee D, Chiu Y, Ma S, et al.
PLoS One
. 2011 May;
6(5):e19804.
PMID: 21603625
Recent evidence suggested that prostate cancer stem/progenitor cells (CSC) are responsible for cancer initiation as well as disease progression. Unfortunately, conventional therapies are only effective in targeting the more differentiated...
4.
Chua C, Chiu Y, Yuen H, Chan K, Wang X, Ling M, et al.
APMIS
. 2010 Nov;
118(12):918-26.
PMID: 21091772
One of the common features in advanced prostate cancer is bone metastasis. In this study, we investigated the clinical relevance of a bone factor, MSX2, in predicting the metastatic ability...
5.
Luk S, Yap W, Chiu Y, Lee D, Ma S, Lee T, et al.
Int J Cancer
. 2010 Jul;
128(9):2182-91.
PMID: 20617516
Emerging evidence supports that prostate cancer originates from a rare subpopulation of cells, namely prostate cancer stem cells (CSCs). Conventional therapies for prostate cancer are believed to mainly target the...
6.
Chua C, Chiu Y, Yuen H, Chan K, Man K, Wang X, et al.
Clin Cancer Res
. 2009 Jun;
15(13):4322-35.
PMID: 19509141
Purpose: Previously, FTY720 was found to possess potent anticancer effects on various types of cancer. In the present study, we aimed to first verify the role of Runx2 in prostate...
7.
Chiu Y, Han H, Leung S, Yuen H, Chau C, Guo Z, et al.
J Mol Biol
. 2008 Nov;
385(2):446-56.
PMID: 19013180
Androgen receptor (AR) is a ligand-dependent transcription factor and its activity is regulated by numerous AR coregulators. Aberrant expression of AR coregulators in prostate cancer cells has an important role...
8.
Yuen H, Chan Y, Cheung W, Wong Y, Wang X, Chan K
Mod Pathol
. 2008 Oct;
21(12):1436-43.
PMID: 18931653
The importance of bone-morphogenetic proteins in prostate cancer is well recognized. Bone-morphogenetic protein-6 overexpression has been shown to increase the aggressiveness and invasiveness of prostate cancer cells. Recent studies on...
9.
Ling M, Chiu Y, Lee T, Leung S, Fung M, Wang X, et al.
J Mol Biol
. 2008 Aug;
382(1):34-43.
PMID: 18674781
Id-1 is a member of the HLH protein family that regulates a wide range of cellular processes such as cell proliferation, apoptosis, senescence and overexpression of Id-1 was recently suggested...
10.
Han H, Wang X, Wang N, Ling M, Wong Y, Yao X
J Agric Food Chem
. 2008 Jul;
56(16):6928-35.
PMID: 18656936
Accumulating epidemiological data suggest that Asian men have lower incidences of prostate cancer and benign prostate hyperplasia (BPH) compared with American and European populations and may have benefited from their...