Yohei Shimono
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Explore the profile of Yohei Shimono including associated specialties, affiliations and a list of published articles.
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Articles
72
Citations
3166
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Recent Articles
1.
Hayashi T, Kumamoto K, Kobayashi T, Hou X, Nagao S, Harada N, et al.
FEBS J
. 2025 Feb;
PMID: 39967403
Estrogen is synthesized throughout various tissues in the body, and its production is regulated by the rate-limiting enzyme aromatase (encoded by the Cyp19a1 gene). Notably, aromatase is also expressed in...
2.
Yoshida J, Hayashi T, Munetsuna E, Khaledian B, Sueishi F, Mizuno M, et al.
Sci Rep
. 2024 Aug;
14(1):18494.
PMID: 39122742
Adipocyte-cancer cell interactions promote tumor development and progression. Previously, we identified adipsin (CFD) and its downstream effector, hepatocyte growth factor (HGF), as adipokines that enhance adipocyte-breast cancer stem cell interactions....
3.
Kotomura N, Shimono Y, Ishihara S
Endocrinology
. 2024 May;
165(6).
PMID: 38717933
CYP19A1 encodes aromatase, which converts testosterone to estrogen, and is induced during placental maturation. To elucidate the molecular mechanism underlying this function, histone methylation was analyzed using the placental cytotrophoblast...
4.
Khaledian B, Thibes L, Shimono Y
Cancer Sci
. 2023 Aug;
114(11):4134-4144.
PMID: 37622414
Cancer stem cells (CSCs) are a highly tumorigenic subpopulation of the cancer cells within a tumor that drive tumor initiation, progression, and therapy resistance. In general, stem cell niche provides...
5.
Toriuchi K, Kihara T, Aoki H, Kakita H, Takeshita S, Ueda H, et al.
Int J Mol Sci
. 2023 Feb;
24(3).
PMID: 36769149
Atherosclerosis can lead to cardiovascular and cerebrovascular diseases. Atherosclerotic plaque formation is promoted by the accumulation of inflammatory cells. Therefore, modulating monocyte recruitment represents a potential therapeutic strategy. In an...
6.
Nouchi Y, Munetsuna E, Yamada H, Yamazaki M, Ando Y, Mizuno G, et al.
Exp Clin Endocrinol Diabetes
. 2022 Nov;
130(12):814-820.
PMID: 36368682
The consumption of high-fructose corn syrup (HFCS) has been increasing in recent decades, especially among children. Some reports suggest that children and adolescents are more sensitive to the adverse effects...
7.
Kageyama I, Yamada H, Munetsuna E, Yamazaki M, Ando Y, Mizuno G, et al.
PLoS One
. 2022 Jun;
17(6):e0270144.
PMID: 35714129
Consumption of fructose-containing beverages such as high-fructose corn syrup (HFCS) is increasing, raising concerns about the negative effects of excessive fructose intake. A recent report indicated that excess HFCS intake...
8.
Hisamori S, Mukohyama J, Koul S, Hayashi T, Rothenberg M, Maeda M, et al.
J Gastroenterol
. 2022 Mar;
57(6):407-422.
PMID: 35244768
Background: MicroRNAs (miRNAs) are key regulators of stem cell functions, including self-renewal and differentiation. In this study, we aimed to identify miRNAs that are upregulated during terminal differentiation in the...
9.
Munetsuna E, Yamada H, Yamazaki M, Ando Y, Mizuno G, Hattori Y, et al.
FASEB J
. 2021 Nov;
35(12):e22030.
PMID: 34748238
Given that fructose consumption has increased by more than 10-fold in recent decades, it is possible that excess maternal fructose consumption causes harmful effects in the next generation. This study...
10.
Mizuno M, Khaledian B, Maeda M, Hayashi T, Mizuno S, Munetsuna E, et al.
Cancers (Basel)
. 2021 Aug;
13(16).
PMID: 34439392
Adipose tissue is a component of the tumor microenvironment and is involved in tumor progression. We have previously shown that adipokine adipsin (CFD) functions as an enhancer of tumor proliferation...