Junko Mukohyama
Overview
Explore the profile of Junko Mukohyama including associated specialties, affiliations and a list of published articles.
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17
Citations
174
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Recent Articles
1.
Matsubara J, Li Y, Koul S, Mukohyama J, Salazar L, Isobe T, et al.
bioRxiv
. 2025 Feb;
PMID: 39896677
Background: (CRCs) are seldom eradicated by cytotoxic chemotherapy. Cancer cells with stem-like functional properties, often referred to as "" (CSCs), display preferential resistance to several anti-tumor agents used in cancer...
2.
Mukohyama J, Koizumi M, Yamashita K, Yoshimi A, Shida D, Kakeji Y
Anticancer Res
. 2024 Jul;
44(8):3553-3556.
PMID: 39060046
Background/aim: Caudal-type homeobox transcription factor 2 (CDX2) is a master regulator of intestinal development and maintenance of the intestinal epithelium. We previously revealed that CDX2 colorectal cancers (CRCs) were associated...
3.
Mukohyama J, Agawa K, Yamashita K, Matsuda T, Shinoda M, Itano O, et al.
Anticancer Res
. 2023 Jul;
43(8):3763-3767.
PMID: 37500172
Background/aim: Colorectal cancer (CRC) with reduced expression of the homeobox transcription factor CDX2, a master gene essential for the development and maintenance of the intestinal tract, is known as a...
4.
Hisamori S, Mukohyama J, Koul S, Hayashi T, Rothenberg M, Maeda M, et al.
J Gastroenterol
. 2022 Mar;
57(6):407-422.
PMID: 35244768
Background: MicroRNAs (miRNAs) are key regulators of stem cell functions, including self-renewal and differentiation. In this study, we aimed to identify miRNAs that are upregulated during terminal differentiation in the...
5.
De Munck S, Provost M, Kurikawa M, Omori I, Mukohyama J, Felix J, et al.
Nature
. 2021 Oct;
600(7887):143-147.
PMID: 34646012
Anaplastic lymphoma kinase (ALK) and the related leukocyte tyrosine kinase (LTK) are recently deorphanized receptor tyrosine kinases. Together with their activating cytokines, ALKAL1 and ALKAL2 (also called FAM150A and FAM150B...
6.
Agawa K, Yamashita K, Nakagawa A, Yamada K, Watanabe A, Mukohyama J, et al.
Anticancer Res
. 2021 Jul;
41(8):4117-4126.
PMID: 34281882
Background/aim: Cancer stem cells (CSCs) contribute to resistance against neoadjuvant chemotherapy (NAC) in esophageal squamous cell carcinoma (ESCC). We conducted a retrospective observational study for the relationship between the expression...
7.
Ueta K, Matsuda T, Yamashita K, Hasegawa H, Mukohyama J, Yamamoto M, et al.
Anticancer Res
. 2019 Oct;
39(10):5767-5772.
PMID: 31570480
Background/aim: To investigate the impact of inguinal lymph node dissection (ILND) following neoadjuvant chemoradiotherapy (NACRT) for rectal cancer patients with ILN metastasis. Patients And Methods: Forty-three patients with rectal cancer...
8.
Mukohyama J, Isobe T, Hu Q, Hayashi T, Watanabe T, Maeda M, et al.
Cancer Res
. 2019 Aug;
79(20):5151-5158.
PMID: 31416845
miRNAs are key players in the integrated regulation of cellular processes and shape many of the functional properties that define the "cancer stem cell" (CSC) phenotype. Little is known, however,...
9.
Yamashita K, Matsuda T, Hasegawa H, Mukohyama J, Arimoto A, Tanaka T, et al.
Ann Gastroenterol Surg
. 2019 Jan;
3(1):24-33.
PMID: 30697607
Neoadjuvant chemoradiotherapy (nCRT) has been widely used as a multidisciplinary approach for stage II/III rectal cancer. However, its safety and efficacy are controversial because previous studies have shown conflicting outcomes....
10.
Mukohyama J, Sumi Y, Kanemitsu K, Hasegawa H, Yamamoto M, Kanaji S, et al.
Int J Surg Case Rep
. 2018 Oct;
52:120-124.
PMID: 30343260
Introduction: Primary appendiceal cancer with fistula formation is extremely rare. We report a case of a patient with appendiceal cancer invading the ileum who underwent successful laparoscopic ileocecal resection. Presentation...