Yohei Katsuyama
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Explore the profile of Yohei Katsuyama including associated specialties, affiliations and a list of published articles.
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723
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Recent Articles
11.
Kawai S, Hagihara R, Shin-Ya K, Katsuyama Y, Ohnishi Y
Angew Chem Int Ed Engl
. 2022 Sep;
61(45):e202211728.
PMID: 36115045
The diazo group is an important functional group that can confer biological activity to natural products owing to its high reactivity. Recent studies have revealed that diazo groups are synthesized...
12.
Chen A, Mindrebo J, Davis T, Kim W, Katsuyama Y, Jiang Z, et al.
Acta Crystallogr D Struct Biol
. 2022 Sep;
78(Pt 9):1171-1179.
PMID: 36048156
Ketosynthases (KSs) catalyse essential carbon-carbon bond-forming reactions in fatty-acid biosynthesis using a two-step, ping-pong reaction mechanism. In Escherichia coli, there are two homodimeric elongating KSs, FabB and FabF, which possess...
13.
Niimi-Nakamura S, Kawaguchi H, Uematsu K, Teramura H, Nakamura-Tsuruta S, Kashiwagi N, et al.
J Gen Appl Microbiol
. 2022 Jul;
68(2):109-116.
PMID: 35831135
The aromatic compound 3-amino-4-hydroxybenzoic acid (3,4-AHBA) can be employed as a raw material for high-performance industrial plastics. The aim of this study is to produce 3,4-AHBA via a recombinant Streptomyces...
14.
Tsutsumi H, Urano N, Katsuyama Y, Ohnishi Y
Biosci Biotechnol Biochem
. 2022 Jun;
86(9):1270-1275.
PMID: 35767877
Terpenoids are the largest class of natural products and are derived from C5 isoprene units. Recent discoveries of modification enzymes in native isoprene units before cyclization or transfer reactions have...
15.
Kawai S, Katsuyama Y, Ohnishi Y
Chembiochem
. 2022 Feb;
23(7):e202100700.
PMID: 35132756
During the biosynthesis of alazopeptin, a tripeptide composed of two molecules of 6-diazo-5-oxo-L-norleucine (DON) and one of alanine, the α/β hydrolase AzpM synthesizes the DON-DON dipeptide using DON tethered to...
16.
Ogawa Y, Katsuyama Y, Ohnishi Y
ACS Synth Biol
. 2021 Dec;
11(1):473-485.
PMID: 34964613
Deep mutational scanning is a method for protein engineering. Here, we applied it to alter the ligand specificity of the transcriptional regulator XylS from to recognize toluic acid instead of...
17.
Tsutsumi H, Katsuyama Y, Tezuka T, Miyano R, Inahashi Y, Takahashi Y, et al.
Chembiochem
. 2021 Nov;
23(3):e202100517.
PMID: 34767291
Indolizidine alkaloids, which have versatile bioactivities, are produced by various organisms. Although the biosynthesis of some indolizidine alkaloids has been studied, the enzymatic machinery for their biosynthesis in Streptomyces remains...
18.
Tsutsumi H, Moriwaki Y, Terada T, Shimizu K, Shin-Ya K, Katsuyama Y, et al.
Angew Chem Int Ed Engl
. 2021 Oct;
61(1):e202111217.
PMID: 34626048
Prenyl pyrophosphate methyltransferases enhance the structural diversity of terpenoids. However, the molecular basis of their catalytic mechanisms is poorly understood. In this study, using multiple strategies, we characterized a geranyl...
19.
Tomita H, Katsuyama Y, Ohnishi Y
J Ind Microbiol Biotechnol
. 2021 Aug;
48(9-10).
PMID: 34453549
Nitroaromatic compounds are essential materials for chemical industry, but they are also potentially toxic environmental pollutants. Therefore, their sensitive detection and degradation are important concerns. The microbial degradation pathways of...
20.
Katsuyama Y, Sone K, Harada A, Kawai S, Urano N, Adachi N, et al.
Angew Chem Int Ed Engl
. 2021 Mar;
60(26):14554-14562.
PMID: 33783097
Nonribosomal peptide synthetases (NRPSs) are attractive targets for bioengineering to generate useful peptides. FmoA3 is a single modular NRPS composed of heterocyclization (Cy), adenylation (A), and peptidyl carrier protein (PCP)...