Motoki Takagi
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Explore the profile of Motoki Takagi including associated specialties, affiliations and a list of published articles.
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Articles
133
Citations
1274
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Recent Articles
1.
Takagi K, Takagi M, Hiyama G, Goda K
Sci Rep
. 2024 Oct;
14(1):22769.
PMID: 39354045
Genotypic and phenotypic diversity, which generates heterogeneity during disease evolution, is common in cancer. The identification of features specific to each patient and tumor is central to the development of...
2.
Homma M, Nakato R, Niida A, Bando M, Fujiki K, Yokota N, et al.
Life Sci Alliance
. 2023 Oct;
7(1).
PMID: 37907238
Nuclear expression of protein kinase CK2α is reportedly elevated in human carcinomas, but mechanisms underlying its variable localization in cells are poorly understood. This study demonstrates a functional connection between...
3.
Kasahara Y, Tamamura S, Hiyama G, Takagi M, Nakamichi K, Doi Y, et al.
Int J Mol Sci
. 2023 Sep;
24(18).
PMID: 37762164
We have developed a highly sensitive promoter trap vector system using transposons to generate reporter cells with high efficiency. Using an EGFP/luciferase reporter cell clone responsive to forskolin, which is...
4.
Koguchi T, Shimizu F, Nagame T, Goto Y, Iwasaki H, Hanafusa A, et al.
Int J Comput Assist Radiol Surg
. 2023 Feb;
18(5):877-885.
PMID: 36809456
The tumor resection ratio must be improved due the increased possibility of recurrence or malignancy. The purpose of this study was to develop a system that includes forceps with a...
5.
Takagi R, Osada K, Hanafusa A, Takagi M, Mohamaddan S, Mitsui K, et al.
Int J Comput Assist Radiol Surg
. 2023 Jan;
18(4):763-773.
PMID: 36689147
Purpose: There is a growing interest in minimally invasive surgery as interventional radiology (IVR), which decreases the burden on a patient. However, occupational exposure is a problem because the treatment...
6.
Ishikawa K, Tamamura S, Takahashi N, Takagi M, Semba K, Watanabe S
Int J Mol Sci
. 2022 Aug;
23(16).
PMID: 36012634
Previously, we established a highly sensitive promoter-trapping vector system using the transposon for the efficient isolation of reporter cells. Herein, we examine whether this screening system can be applied to...
7.
Sasaki K, Suzuki M, Sonoda T, Schneider-Poetsch T, Ito A, Takagi M, et al.
Cell Chem Biol
. 2022 Jun;
29(7):1153-1161.e5.
PMID: 35728598
Histone lysine methylation is an epigenetic mark that can control gene expression. In particular, H3K9me3 contributes to transcriptional repression by regulating chromatin structure. Successful mitotic progression requires correct timing of...
8.
Higa A, Takahashi N, Hiyama G, Tamura H, Hoshi H, Shimomura K, et al.
J Vis Exp
. 2021 Jun;
(172).
PMID: 34180908
Patient-derived tumor organoids (PDOs) are expected to be a preclinical cancer model with better reproducibility of disease than traditional cell culture models. PDOs have been successfully generated from a variety...
9.
Takahashi N, Higa A, Hiyama G, Tamura H, Hoshi H, Dobashi Y, et al.
Oncol Lett
. 2021 Apr;
21(5):406.
PMID: 33841567
An assay system using patient-derived tumor models represents a promising preclinical cancer model that replicates the disease better than traditional cell culture models. Patient-derived tumor organoid (PDO) and patient-derived tumor...
10.
Takahashi N, Hoshi H, Higa A, Hiyama G, Tamura H, Ogawa M, et al.
Cells
. 2019 May;
8(5).
PMID: 31137590
Patient-derived tumor organoids (PDOs) represent a promising preclinical cancer model that better replicates disease, compared with traditional cell culture models. We have established PDOs from various human tumors to accurately...