Yoan Machado
Overview
Explore the profile of Yoan Machado including associated specialties, affiliations and a list of published articles.
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20
Citations
290
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Recent Articles
11.
Machado Y, Duinkerken S, Hoepflinger V, Mayr M, Korotchenko E, Kurtaj A, et al.
J Control Release
. 2017 Sep;
266:87-99.
PMID: 28919557
Due to its unique immunological properties, the skin is an attractive target tissue for allergen-specific immunotherapy. In our current work, we combined a dendritic cell targeting approach with epicutaneous immunization...
12.
Kurtaj A, Hillebrand C, Fichtinger G, Hattinger E, Lietzenmayer M, Machado Y, et al.
J Allergy Clin Immunol
. 2017 Sep;
140(6):1746-1749.e11.
PMID: 28867457
No abstract available.
13.
Scheiblhofer S, Laimer J, Machado Y, Weiss R, Thalhamer J
Expert Rev Vaccines
. 2017 Mar;
16(5):479-489.
PMID: 28290225
In modern vaccinology and immunotherapy, recombinant proteins more and more replace whole organisms to induce protective or curative immune responses. Structural stability of proteins is of crucial importance for efficient...
14.
Cruz-Leal Y, Lopez-Requena A, Lopetegui-Gonzalez I, Machado Y, Alvarez C, Perez R, et al.
Front Immunol
. 2016 Oct;
7:374.
PMID: 27713745
Liposomes containing phosphatidylcholine have been widely used as adjuvants. Recently, we demonstrated that B-1 cells produce dipalmitoyl-phosphatidylcholine (DPPC)-specific IgM upon immunization of BALB/c mice with DPPC-liposomes encapsulating ovalbumin (OVA). Although...
15.
Scheiblhofer S, Machado Y, Feinle A, Thalhamer J, Husing N, Weiss R
Expert Opin Drug Deliv
. 2016 Jun;
13(12):1777-1788.
PMID: 27321476
Allergen-specific immunotherapy is the only curative approach for the treatment of allergies. There is an urgent need for improved therapies, which increase both, efficacy and patient compliance. Novel routes of...
16.
Garcia-Fernandez R, Ziegelmuller P, Gonzalez L, Mansur M, Machado Y, Redecke L, et al.
Protein Expr Purif
. 2016 Mar;
123:42-50.
PMID: 26993255
The major protease inhibitor from the sea anemone Stichodactyla helianthus (ShPI-1) is a non-specific inhibitor that binds trypsin and other trypsin-like enzymes, as well as chymotrypsin, and human neutrophil elastase....
17.
Machado Y, Freier R, Scheiblhofer S, Thalhamer T, Mayr M, Briza P, et al.
J Allergy Clin Immunol
. 2015 Nov;
137(5):1525-34.
PMID: 26559323
Background: The search for intrinsic factors, which account for a protein's capability to act as an allergen, is ongoing. Fold stability has been identified as a molecular feature that affects...
18.
Cruz-Leal Y, Machado Y, Lopez-Requena A, Canet L, Laborde R, Alvares A, et al.
Int Immunol
. 2014 Mar;
26(8):427-37.
PMID: 24618118
B-1 lymphocytes comprise a unique subset of B cells that differ phenotypically, ontogenetically and functionally from conventional B-2 cells. A frequent specificity of the antibody repertoire of peritoneal B-1 cells...
19.
Weiss R, Scheiblhofer S, Machado Y, Thalhamer J
Curr Opin Allergy Clin Immunol
. 2013 Oct;
13(6):669-76.
PMID: 24169433
Purpose Of Review: This review summarizes recent preclinical and human studies evaluating allergen-specific immunotherapy via the transcutaneous route, and provides a rationale for the application of modified allergens with reduced...
20.
Ramos Y, Gutierrez E, Machado Y, Sanchez A, Castellanos-Serra L, Gonzalez L, et al.
J Proteome Res
. 2008 Apr;
7(6):2427-34.
PMID: 18422305
Here we demonstrate the usefulness of peptide fractionation by SDS-free polyacrylamide gel electrophoresis and its applicability to proteomics studies. In the absence of SDS, the driving force for the electrophoretic...