Isabel Pablos
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Explore the profile of Isabel Pablos including associated specialties, affiliations and a list of published articles.
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13
Citations
126
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Recent Articles
1.
Grin P, Baid K, de Jesus H, Kozarac N, Bell P, Jiang S, et al.
Cell Rep
. 2024 Dec;
43(12):115080.
PMID: 39673710
SARS-CoV-2 3C-like protease (3CL or M) cleaves the SARS-CoV-2 polyprotein and >300 intracellular host proteins to enhance viral replication. By lytic cell death following gasdermin (GSDM) pore formation in cell...
2.
Cesar Ramos de Jesus H, Solis N, Machado Y, Pablos I, Bell P, Kappelhoff R, et al.
J Virol
. 2024 May;
98(6):e0004924.
PMID: 38742901
SARS-CoV-2 3C-like main protease (3CL) is essential for protein excision from the viral polyprotein. 3CL inhibitor drug development to block SARS-CoV-2 replication focuses on the catalytic non-prime (P) side for...
3.
Zabel M, Weber M, Kratzer B, Kohler C, Jahn-Schmid B, Gadermaier G, et al.
J Allergy Clin Immunol
. 2022 Jun;
150(4):920-930.
PMID: 35738928
Background: Worldwide, pollen of the weed mugwort (Artemisiavulgaris) is a major cause of severe respiratory allergy, with its major allergen, Art v 1, being the key pathogenic molecule for millions...
4.
Wangorsch A, Jamin A, Eichhorn S, Pablos I, Sharma S, Schweidler B, et al.
Front Allergy
. 2022 Apr;
2:691627.
PMID: 35386988
Manifestation of respiratory allergy to American cockroach () is prominent in the subtropical and tropical areas. However, co-existing perennial indoor inhalant allergies frequently compromise clinical diagnosis of cockroach allergy, and...
5.
Pablos I, Machado Y, de Jesus H, Mohamud Y, Kappelhoff R, Lindskog C, et al.
Cell Rep
. 2021 Oct;
37(4):109892.
PMID: 34672947
The main viral protease (3CL) is indispensable for SARS-CoV-2 replication. We delineate the human protein substrate landscape of 3CL by TAILS substrate-targeted N-terminomics. We identify more than 100 substrates in...
6.
Pablos I, Egger M, Vejvar E, Reichl V, Briza P, Zennaro D, et al.
Medicina (Kaunas)
. 2019 Aug;
55(8).
PMID: 31434264
Pollens of weeds are relevant elicitors of type I allergies. While many species occur worldwide, allergy research so far has only focused on . We aimed to characterize other prevalent...
7.
Eichhorn S, Horschlager A, Steiner M, Laimer J, Jensen B, Versteeg S, et al.
Mol Nutr Food Res
. 2019 Jun;
63(18):e1900336.
PMID: 31207117
Scope: Allergies to lipid transfer proteins involve severe adverse reactions; thus, effective and sustainable therapies are desired. Previous attempts disrupting disulfide bonds failed to maintain immunogenicity; thus, the aim is...
8.
Schulke S, Kuttich K, Wolfheimer S, Duschek N, Wangorsch A, Reuter A, et al.
Sci Rep
. 2018 Feb;
8(1):2745.
PMID: 29410477
A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper.
9.
Schulke S, Kuttich K, Wolfheimer S, Duschek N, Wangorsch A, Reuter A, et al.
Sci Rep
. 2017 Sep;
7(1):11782.
PMID: 28924222
Allergies to weed pollen including members of the Compositae family, such as mugwort, ragweed, and feverfew are spreading worldwide. To efficiently treat these newly arising allergies, allergen specific immunotherapy needs...
10.
Machado Y, Duinkerken S, Hoepflinger V, Mayr M, Korotchenko E, Kurtaj A, et al.
J Control Release
. 2017 Sep;
266:87-99.
PMID: 28919557
Due to its unique immunological properties, the skin is an attractive target tissue for allergen-specific immunotherapy. In our current work, we combined a dendritic cell targeting approach with epicutaneous immunization...