Yiling Bi
Overview
Explore the profile of Yiling Bi including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
86
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0
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Recent Articles
1.
Acevedo J, Bi Y, Gee J, Khatwani S
Mol Ther Methods Clin Dev
. 2024 Sep;
32(3):101332.
PMID: 39297126
[This corrects the article DOI: 10.1016/j.omtm.2024.101321.].
2.
Acevedo J, Bi Y, Gee J, Khatwani S
Mol Ther Methods Clin Dev
. 2024 Sep;
32(3):101321.
PMID: 39282080
A rigorous analytical assessment of recombinant adeno-associated virus (rAAV)-based drug products is critical for their successful development as clinical candidates. It is especially important to ascertain high purity while simultaneously...
3.
Kalita M, Joice A, Le K, Bi Y, Ramamoorthy G, Antelope O, et al.
Methods Mol Biol
. 2021 Oct;
2303:687-694.
PMID: 34626416
Glycosaminoglycans (GAGs) play crucial roles in several biological processes including cell division, angiogenesis, anticoagulation, neurogenesis, axon guidance and growth, and viral and bacterial infections among others. The GAG cleaving hydrolases/lyases...
4.
Bi Y, Le K, Ramamoorthy G, Kuberan B
SLAS Technol
. 2020 Jun;
25(4):397-403.
PMID: 32589074
Heparin has been in clinical use as an anticoagulant for the last eight decades and used worldwide in more than 100 million medical procedures every year. This lifesaving drug is...
5.
Sankaranarayanan N, Bi Y, Kuberan B, Desai U
Comput Struct Biotechnol J
. 2020 Apr;
18:933-941.
PMID: 32346466
Pharmaceutical heparin's activity arises from a key high affinity and high selectivity antithrombin binding motif, which forms the basis for its use as an anticoagulant. The current problems with the...
6.
Owings K, Lowry J, Bi Y, Might M, Chow C
Hum Mol Genet
. 2018 Jan;
27(6):1055-1066.
PMID: 29346549
Autosomal recessive loss-of-function mutations in N-glycanase 1 (NGLY1) cause NGLY1 deficiency, the only known human disease of deglycosylation. Patients present with developmental delay, movement disorder, seizures, liver dysfunction and alacrima....
7.
Mencio C, Garud D, Doi Y, Bi Y, Vankayalapati H, Koketsu M, et al.
Bioorg Med Chem Lett
. 2017 Oct;
27(22):5027-5030.
PMID: 29033235
Xylosides are small molecules that serve as primers of glycosaminoglycan biosynthesis. Xyloside mediated modulation of biological functions depends on the extent of priming activity and fine structures of primed GAG...
8.
Bi Y, Might M, Vankayalapati H, Kuberan B
Bioorg Med Chem Lett
. 2017 May;
27(13):2962-2966.
PMID: 28512024
N-Glycanase deficiency, or NGLY1 deficiency, is an extremely rare human genetic disease. N-Glycanase, encoded by the gene NGLY1, is an important enzyme involved in protein deglycosylation of misfolded proteins. Deglycosylation...
9.
Liu Y, Gao F, Jiang H, Niu L, Bi Y, Young C, et al.
Cancer Lett
. 2013 May;
337(1):66-76.
PMID: 23693077
Retigeric acid B (RB) has been reported to exhibit its anti-tumor activity in vitro and in vivo. Here, we found that RB significantly inhibited activity of topoisomerase IIα (Topo IIα),...
10.
Li Y, Bi Y, Xi Y, Li L
J Drug Target
. 2012 Nov;
21(2):188-99.
PMID: 23126604
The aim of the present study is to synthesize Pluronic F127-polyethylenimine-folate (PF127-PEI-FA) copolymer, construct a mixed micelle system with PF127-PEI-FA copolymer and Pluronic P123 (PP123) and to evaluate the potential...