Yeyejide Adeleye
Overview
Explore the profile of Yeyejide Adeleye including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
9
Citations
148
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Janowska-Sejda E, Adeleye Y, Currie R
Front Toxicol
. 2022 Mar;
3:806311.
PMID: 35295108
The identification of developmental and reproductive toxicity (DART) is a critical component of toxicological evaluations of chemical safety. Adverse Outcome Pathways (AOPs) provide a framework to describe biological processes leading...
2.
Sun B, Ross S, Rowley S, Adeleye Y, Clewell R
Environ Mol Mutagen
. 2017 Feb;
58(2):72-83.
PMID: 28195382
p53 is a key integrator of cellular response to DNA damage, supporting post-translational repair and driving transcription-mediated responses including cell cycle arrest, apoptosis, and repair. DNA damage sensing kinases recognize...
3.
Clewell R, McMullen P, Adeleye Y, Carmichael P, Andersen M
Adv Exp Med Biol
. 2016 Sep;
856:205-230.
PMID: 27671724
The field of toxicity testing for non-pharmaceutical chemicals is in flux with multiple initiatives in North America and the EU to move away from animal testing to mode-of-action based in...
4.
Klapacz J, Pottenger L, Engelward B, Heinen C, Johnson G, Clewell R, et al.
Mutat Res Rev Mutat Res
. 2016 Apr;
767:77-91.
PMID: 27036068
From a risk assessment perspective, DNA-reactive agents are conventionally assumed to have genotoxic risks at all exposure levels, thus applying a linear extrapolation for low-dose responses. New approaches discussed here,...
5.
Clewell R, Sun B, Adeleye Y, Carmichael P, Efremenko A, McMullen P, et al.
Toxicol Sci
. 2014 Aug;
142(1):56-73.
PMID: 25078064
As part of a larger effort to provide proof-of-concept in vitro-only risk assessments, we have developed a suite of high-throughput assays for key readouts in the p53 DNA damage response...
6.
Adeleye Y, Andersen M, Clewell R, Davies M, Dent M, Edwards S, et al.
Toxicology
. 2014 Mar;
332:102-11.
PMID: 24582757
Risk assessment methodologies in toxicology have remained largely unchanged for decades. The default approach uses high dose animal studies, together with human exposure estimates, and conservative assessment (uncertainty) factors or...
7.
Li Z, Sun B, Clewell R, Adeleye Y, Andersen M, Zhang Q
Toxicol Sci
. 2013 Nov;
137(2):371-84.
PMID: 24241721
The 2007 National Research Council Report "Toxicity Testing in the 21st Century: A Vision and A Strategy" recommended an integrated, toxicity pathway-oriented approach for chemical testing. As an integral component...
8.
Kleensang A, Maertens A, Rosenberg M, Fitzpatrick S, Lamb J, Auerbach S, et al.
ALTEX
. 2013 Oct;
31(1):53-61.
PMID: 24127042
Despite wide-spread consensus on the need to transform toxicology and risk assessment in order to keep pace with technological and computational changes that have revolutionized the life sciences, there remains...
9.
Svensson J, Pesudo L, McRee S, Adeleye Y, Carmichael P, Samson L
PLoS One
. 2013 Sep;
8(9):e73736.
PMID: 24040048
Toxicity screening of compounds provides a means to identify compounds harmful for human health and the environment. Here, we further develop the technique of genomic phenotyping to improve throughput while...