Yehudit Hasin
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Explore the profile of Yehudit Hasin including associated specialties, affiliations and a list of published articles.
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9
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1198
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Recent Articles
1.
Ma F, Fuqua B, Hasin Y, Yukhtman C, Vulpe C, Lusis A, et al.
BMC Genomics
. 2019 Jan;
20(1):9.
PMID: 30616562
Background: 3' RNA sequencing provides an alternative to whole transcript analysis. However, we do not know a priori the relative advantage of each method. Thus, a comprehensive comparison between the...
2.
Kurt Z, Barrere-Cain R, LaGuardia J, Mehrabian M, Pan C, Hui S, et al.
Biol Sex Differ
. 2018 Oct;
9(1):46.
PMID: 30343673
Background: Non-alcoholic fatty liver disease (NAFLD) encompasses benign steatosis and more severe conditions such as non-alcoholic steatohepatitis (NASH), cirrhosis, and liver cancer. This chronic liver disease has a poorly understood...
3.
Hasin Y, Seldin M, Lusis A
Genome Biol
. 2017 May;
18(1):83.
PMID: 28476144
High-throughput technologies have revolutionized medical research. The advent of genotyping arrays enabled large-scale genome-wide association studies and methods for examining global transcript levels, which gave rise to the field of...
4.
Lagarrigue S, Hormozdiari F, Martin L, Lecerf F, Hasin Y, Rau C, et al.
Genetics
. 2013 Feb;
193(4):1107-15.
PMID: 23410828
Several studies have investigated RNA-DNA differences (RDD), presumably due to RNA editing, with conflicting results. We report a rigorous analysis of RDD in exonic regions in mice, taking into account...
5.
Waszak S, Hasin Y, Zichner T, Olender T, Keydar I, Khen M, et al.
PLoS Comput Biol
. 2010 Nov;
6(11):e1000988.
PMID: 21085617
Copy-number variations (CNVs) are widespread in the human genome, but comprehensive assignments of integer locus copy-numbers (i.e., copy-number genotypes) that, for example, enable discrimination of homozygous from heterozygous CNVs, have...
6.
Hasin Y, Olender T, Khen M, Gonzaga-Jauregui C, Kim P, Urban A, et al.
PLoS Genet
. 2008 Nov;
4(11):e1000249.
PMID: 18989455
Olfactory receptors (ORs), which are involved in odorant recognition, form the largest mammalian protein superfamily. The genomic content of OR genes is considerably reduced in humans, as reflected by the...
7.
Menashe I, Abaffy T, Hasin Y, Goshen S, Yahalom V, Luetje C, et al.
PLoS Biol
. 2007 Nov;
5(11):e284.
PMID: 17973576
The genetic basis of odorant-specific variations in human olfactory thresholds, and in particular of enhanced odorant sensitivity (hyperosmia), remains largely unknown. Olfactory receptor (OR) segregating pseudogenes, displaying both functional and...
8.
Hasin Y, Avidan N, Bercovich D, Korczyn A, Silman I, Beckmann J, et al.
Curr Alzheimer Res
. 2005 Jun;
2(2):207-18.
PMID: 15974920
Acetylcholinesterase (AChE) plays a crucial physiological role in termination of impulse transmission at cholinergic synapses through rapid hydrolysis of acetylcholine. In addition, it was implicated in amyloid plaque formation, a...
9.
Hasin Y, Avidan N, Bercovich D, Korczyn A, Silman I, Beckmann J, et al.
Hum Mutat
. 2004 Oct;
24(5):408-16.
PMID: 15459952
Acetylcholinesterase (AChE) plays a crucial physiological role in termination of impulse transmission at cholinergic synapses through rapid hydrolysis of acetylcholine. It is a highly conserved molecule, and only a few...