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Yee Mon Thu

Explore the profile of Yee Mon Thu including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 523
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Recent Articles
1.
Thu Y
Nucleus . 2024 Sep; 15(1):2398450. PMID: 39287196
Sumoylation, a process in which SUMO (small ubiquitin like modifier) is conjugated to target proteins, emerges as a post-translational modification that mediates protein-protein interactions, protein complex assembly, and localization of...
2.
Herce-Hagiwara B, Thu Y
MicroPubl Biol . 2021 Sep; 2021. PMID: 34585105
Sgs1p in belongs to the RecQ helicase family. Sgs1p is involved in recombination during DNA damage repair and sumoylation of Sgs1p is one mechanism by which the protein is regulated....
3.
Thu Y, French L, Hersh B, Nelson M, Whitenack L
Integr Comp Biol . 2021 Jun; 61(3):944-956. PMID: 34113995
Incorporating active research opportunities into undergraduate curricula is one of the most cited elements demonstrated to improve inclusive excellence and retention in all STEM fields. Allegheny College has a long...
4.
Thu Y
Genetics . 2020 Oct; 216(2):333-342. PMID: 33023931
Recent work by Kentaro Ohkuni and colleagues exemplifies how a series of molecular mechanisms contribute to a cellular outcome-equal distribution of chromosomes. Failure to maintain structural and numerical integrity of...
5.
Becker J, Gallo D, Leung W, Croissant T, Thu Y, Nguyen H, et al.
Nucleic Acids Res . 2018 May; 46(11):5634-5650. PMID: 29741650
Overexpression of the flap endonuclease FEN1 has been observed in a variety of cancer types and is a marker for poor prognosis. To better understand the cellular consequences of FEN1...
6.
Thu Y, Van Riper S, Higgins L, Zhang T, Becker J, Markowski T, et al.
Cell Rep . 2016 May; 15(6):1254-65. PMID: 27134171
Loss of minichromosome maintenance protein 10 (Mcm10) causes replication stress. We uncovered that S. cerevisiae mcm10-1 mutants rely on the E3 SUMO ligase Mms21 and the SUMO-targeted ubiquitin ligase complex...
7.
Thu Y, Bielinsky A
Semin Cell Dev Biol . 2014 Mar; 30:121-30. PMID: 24662891
Minichromsome maintenance protein 10 (Mcm10) is an essential replication factor that is required for the activation of the Cdc45:Mcm2-7:GINS helicase. Mcm10's ability to bind both ds and ssDNA appears vital...
8.
Nguyen H, Becker J, Thu Y, Costanzo M, Koch E, Smith S, et al.
PLoS One . 2013 Jul; 8(6):e66379. PMID: 23824283
Deficiency in DNA ligase I, encoded by CDC9 in budding yeast, leads to the accumulation of unligated Okazaki fragments and triggers PCNA ubiquitination at a non-canonical lysine residue. This signal...
9.
Thu Y, Bielinsky A
Trends Biochem Sci . 2013 Jan; 38(4):184-94. PMID: 23332289
Minichromosome maintenance protein 10 (Mcm10) is required for DNA replication in all eukaryotes. Although the exact contribution of Mcm10 to genome replication remains heavily debated, early reports suggested that it...
10.
Thu Y, Richmond A
Cytokine Growth Factor Rev . 2010 Aug; 21(4):213-26. PMID: 20685151
NF-κB inducing kinase (NIK) is a kinase that activates the canonical and non-canonical NF-κB pathways to control transcriptional expression of certain proteins such as cytokines, chemokines and NF-κB signaling molecules....